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Table 2 Cox regression analysis for distantmetastasis-free survival for hypopharyngeal cancer patients (No. of patients = 121)

From: 18F-FDG-PET/CT can be used to predict distant metastasis in hypopharyngeal squamous cell carcinoma

Variables

Univariable analysis

Multivariable analysis

HR

95% CI

P value

HR

95% CI

P value

Gender

Male versus female

0.66

0.20–2.17

0.49

   

Age

≥ 70 versus < 70 years

1.98

0.98–4.01

0.06

   

Primary site

PS versus non-PS

1.01

0.45–2.27

0.98

   

Treatment

Surgery versus radiation

0.85

0.42–1.73

0.66

   

T-classification

T3 + T4 versus T1 + T2

3.37

1.50–7.55

0.003*

1.52

0.65–3.58

0.33

N-classification

N2 + N3 versus N0 + N1

2.96

1.14–7.72

0.026*

1.51

0.20–11.2

0.69

Clinical stage

Stage IV versus I + II + III

3.33

1.17–9.54

0.025*

1.06

0.11–9.85

0.96

SUVmax primary tumor

≥ 13.9 versus < 13.9

12.09

2.88–50.7

0.001*

8.61

1.91–38.8

0.005*

  1. HR: Hazard ratio. 95% CI: 95% confidence interval. SUV max: maximum standard uptake value. P value for null hypothesis; *statistically significant