|
Variable
|
Number
|
5-year OS†
|
p
|
5-year DSS‡
|
p
|
5-year DFS§
|
p
|
|---|
|
(%)
|
(%)
|
(%)
|
|---|
|
Sex
| | | | | | | |
|
Male
|
91
|
77.2
|
0.780
|
80.8
|
0.233
|
66.6
|
0.310
|
|
Female
|
14
|
85.7
| |
92.9
| |
78.6
| |
|
Age
| | | | | | | |
|
< 54
|
50
|
85.7
|
0.140
|
85.7
|
0.134
|
71.9
|
0.281
|
|
≥ 54
|
55
|
71.8
| |
79.3
| |
65.0
| |
|
Smoking habit
| | | | | | | |
|
No
|
19
|
73.3
|
0.656
|
83.1
|
0.606
|
68.0
|
0.782
|
|
Yes
|
86
|
79.7
| |
82.3
| |
68.3
| |
|
Betelnut chewing
| | | | | | | |
|
No
|
22
|
71.0
|
0.603
|
85.2
|
0.511
|
72.4
|
0.473
|
|
Yes
|
83
|
80.3
| |
81.5
| |
67.1
| |
|
Alcohol drinking
| | | | | | | |
|
No
|
26
|
88.5
|
0.213
|
96.0
|
0.086
|
76.3
|
0.331
|
|
Yes
|
79
|
75.2
| |
78.0
| |
65.6
| |
|
pT classification
| | | | | | | |
|
pT1
|
28
|
96.4
|
0.004*
|
96.4
|
0.021*
|
84.6
|
0.023*
|
|
pT2-3
|
77
|
72.2
| |
77.3
| |
62.3
| |
|
Histological grade
| | | | | | | |
|
WDSCC¶
|
38
|
83.9
|
0.743
|
86.5
|
0.839
|
68.3
|
0.309
|
|
MDSCC∥
|
62
|
75.0
| |
80.1
| |
70.6
| |
|
PDSCC#
|
5
|
80.0
| |
80.0
| |
40.0
| |
|
Depth of invasion
| | | | | | | |
|
< 8 mm
|
52
|
84.1
|
0.121
|
88.5
|
0.256
|
74.6
|
0.351
|
|
≥ 8 mm
|
53
|
73.0
| |
76.6
| |
62.1
| |
|
Perineural invasion
| | | | | | | |
|
No
|
71
|
77.7
|
0.528
|
80.9
|
0.405
|
64.3
|
0.128
|
|
Yes
|
34
|
79.3
| |
85.3
| |
76.2
| |
|
Lymphovascular invasion
| | | | | | | |
|
No
|
82
|
78.7
|
0.953
|
81.2
|
0.857
|
66.6
|
0.621
|
|
Yes
|
23
|
77.7
| |
86.7
| |
73.9
| |
|
Surgical margin
| | | | | | | |
|
< 4 mm
|
23
|
71.2
|
0.279
|
71.2
|
0.320
|
60.9
|
0.364
|
|
≥ 4 mm
|
82
|
80.1
| |
85.2
| |
70.3
| |
|
Size of positive node
| | | | | | | |
|
< 1.3 cm
|
42
|
83.1
|
0.431
|
88.1
|
0.224
|
75.8
|
0.182
|
|
≥ 1.3 cm
|
63
|
75.1
| |
78.5
| |
63.3
| |
|
Adjuvant therapy
| | | | | | | |
|
No
|
53
|
72.5
|
0.801
|
78.1
|
0.239
|
63.5
|
0.270
|
|
Yes
|
52
|
84.3
| |
86.5
| |
73.0
| |
- †OS, overall survival; ‡DSS, disease specific survival; §DFS, disease free survival
- ¶WDSCC, well differentiated squamous cell carcinoma
- ∥MDSCC, moderately differentiated squamous cell carcinoma
- #PDSCC, poorly differentiated squamous cell carcinoma
