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Fig. 1 | Journal of Otolaryngology - Head & Neck Surgery

Fig. 1

From: Circ_0000144 acts as a miR-1178-3p decoy to promote cell malignancy and angiogenesis by increasing YWHAH expression in papillary thyroid cancer

Fig. 1

Knockdown of circ_0000144 inhibited cell proliferation and accelerated cell apoptosis in PTC cells. A and B RT-qPCR revealed the expression of circ_0000144 in PTC tissues and cells. *P < 0.05 vs. adjacent normal thyroid tissues or Nthy-ori 3-1 cells. C–I PTC cells were transfected with si-NC or si-circ_0000144. C RT-qPCR validated the interference efficiency of si-circ_0000144 in PTC cells. DF The proliferation and cell cycle progression of PTC cells were analyzed by CCK-8 and flow cytometry assays. G Western blotting detected protein levels of cyclinD1 and p21 in PTC cells. H The apoptosis of PTC cells was surveyed by flow cytometry assay. I Western blotting analyzed protein levels of Bax and Bcl-2 in PTC cells. *P < 0.05 vs. si-NC

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