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Fig. 4 | Journal of Otolaryngology - Head & Neck Surgery

Fig. 4

From: Circ_0000144 acts as a miR-1178-3p decoy to promote cell malignancy and angiogenesis by increasing YWHAH expression in papillary thyroid cancer

Fig. 4

Circ_0000144 was verified as a decoy for miR-1178-3p. A A schematic drawing displayed the putative binding sites between circ_0000144 and miR-1178-3p. B RT-qPCR analysis of miR-1178-3p expression in PTC cells transfected with miR-1178-3p mimic. *P < 0.05 vs. miR-NC. C and D Dual-luciferase reporter assay verified the relationship between miR-1178-3p and circ_000014. E and F RT-qPCR detected the expression of miR-1178-3p in PTC tissues and cells. *P < 0.05 vs. adjacent normal thyroid tissues or Nthy-ori 3-1 cells. G The interference efficiency of anti-miR-1178-3p in PTC cells was verified by RT-qPCR. *P < 0.05 vs. anti-miR-NC. H and I Effect of miR-1178-3p silencing on the expression of miR-1178-3p in si-circ_0000144-transfetced PTC cells was analyzed by RT-qPCR. *P < 0.05 vs. si-NC or si-circ_0000144 + anti-miR-NC

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Journal of Otolaryngology - Head & Neck Surgery

ISSN: 1916-0216

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