Fig. 7

MiR-1178-3p targeted YWHAH to regulate proliferation, apoptosis, migration, invasion, and angiogenesis of PTC cells. A–K PTC cells were transfected with miR-NC, miR-1178-3p, miR-1178-3p + vector, or miR-1178-3p + YWHAH. A–D Analysis of proliferation and cell cycle progression of PTC cells by CCK-8 and flow cytometry assays. E Assessment of protein levels of cyclinD1 and p21 in PTC cells by western blotting. F Detection of the apoptosis of PTC cells by flow cytometry assay. G Measurement of protein levels of Bax and Bcl-2 in PTC cells by western blotting. H–K Analysis of migration, invasion, and angiogenesis of PTC cells by wound-healing, transwell, and tube formation assays. *P < 0.05 vs. miR-NC or miR-1178-3p + vector