Characteristics | Before matching | After matching | ||||
---|---|---|---|---|---|---|
Hemithyroidectomy with RFA | Total thyroidectomy | P value | Hemithyroidectomy with RFA | Total thyroidectomy | P value | |
Cases | 271 | 368 | 191 | 191 | ||
Age at surgery | 41 (21–54) | 42 (25–50) | 0.043 | 32 (24–50) | 34 (21–51) | 0.364 |
Female | 188 (69.4%) | 265 (72.0%) | 0.468 | 103 (53.9%) | 98 (51.3%) | 0.608 |
Primary tumor | ||||||
Right lobe | 154 (56.8%) | 222 (40.8%) | 0.374 | 116 (60.7%) | 109 (57.1%) | 0.467 |
Multifocality | 29 (10.7%) | 41 (11.1%) | 0.860 | 19 (9.9%) | 21 (11.0%) | 0.738 |
Nodule diameter (cm) | 1.4 (1.0 – 3.4) | 1.8 (1.0 – 4.0) | 0.012 | 1.6 (1.0 – 3.5) | 1.7 (1.1 – 4.0) | 0.751 |
Contralateral nodule(s) | ||||||
Multifocality | 84 (31.0%) | 150 (40.7%) | 0.011 | 48 (25.1%) | 51 (26.7%) | 0.656 |
Nodule diameter | 0.8 ± 0.7 | 1.0 ± 0.9 | 0.017 | 0.9 ± 0.8 | 1.0 ± 0.7 | 0.452 |
≥ 1.0 cm | 57 (21.0%) | 114 (31.0%) | 57 (21.0%) | 114 (31.0%) | 0.726 | |
Nodule volume (ml) | 3.0 ± 2.9 | 3.4 ± 2.4 | 0.020 | 3.1 ± 2.6 | 3.3 ± 2.1 | 0.641 |
Pathological lymph node metastasis | 80 (29.5%) | 143 (38.9%) | 0.014 | 62 (32.5%) | 67 (35.1%) | 0.589 |
Serum thyroglobulin (normal: 1.59 – 50.03) (μg/ml) (one month after surgery) | 21.77 (15.03 – 37.79) | 0.07 (0.05–2.23) | 0.247 | 22.81 (16.27 – 34.21) | 0.41 (0..07 – 1.85) | 0.127 |
Median follow-up period | 4.1 years (2.0–5.4) | 4.7 years (2.0–6.1) | 0.024 | 4.1 years (2.0–5.4) | 4.2 years (2.0–5.5) | 0.172 |