Table 4 Multivariable analysis – predictive factors associated with local recurrence free survival

Age of diagnosis (per 5 years)

1.20 (1.09, 1.32)

 < 0.001

Alcohol per week (per 10 drinks)

1.26 (1.16, 1.38)

 < 0.001

Pathologic T stage (vs. T1)

0.003

T2

2.17 (1.20, 3.92)

0.010

T3-4

2.78 (1.55, 5.01)

 < 0.001

Pathologic N stage (vs. N0)

 < 0.001

N1

1.05 (0.51, 2.18)

0.887

N2-N3

2.95 (1.90, 4.58)

 < 0.001