Table 1 The clinical findings, pathologic features and treatment outcomes of the occult neoplasm of facial nerve
From: Bell’s palsy misdiagnosis: characteristics of occult tumors causing facial paralysis
Patient | Sex/age | Final diagnosis | Time to referral (mo) | Initial HB grade | Suspected occult neoplasm | Diagnostic Procedure | Recurrence | Follow-up (mo) | Final outcome |
|---|---|---|---|---|---|---|---|---|---|
Diagnostic delay (mo)* | HB grade at referral | Reason for suspicion | Definitive treatment | ||||||
1 | F/69 | Skin SCC | 13 | 2 | Yes | Facial nerve biopsy (parotidectomy approach) | No | 46 | NED |
24 | 6 | Progressive, irreversible | Chemoradiation treatment | ||||||
2 | M/33 | Parotid ACC | 8 | 5 | No | Facial nerve biopsy (Incidental finding at facial reanimation surgery) | Regional recurrence, POD 40 mo- > Palliative treatment | 68 | AWD until last follow-up |
15 | 5 | Irreversible | Radical parotidectomy with neck dissection, temporal bone resection Postoperative radiation | ||||||
3 | M/58 | Skin SCC | 20 | 4 | Yes | Transoral biopsy of inferior alveolar nerve (multiple cranial nerve invasion) | Stable disease | 22 | AWD |
21 | 5 | Progressive, irreversible | RT | ||||||
4 | M/50 | Parotid ACC | 15 | 2 | Yes | Facial nerve biopsy | Lung metastasis, POD 32 mo-> salvage surgery | 72 | NED |
19 | 6 | Progressive, irreversible | Radical parotidectomy with neck dissection, temporal bone resection postoperative radiation | ||||||
5 | M/54 | Skin SCC | 12 | 2 | Yes | Infraorbital nerve biopsy | Stable disease | 30 | AWD |
21 | 6 | Progressive, irreversible | CCRT | ||||||
6 | M/81 | Skin SCC | 28 | 5 | Yes | Transmastoid biopsy | Progressive disease | 36 | AWD until last follow-up |
34 | 6 | irreversible | Clinical trial† | ||||||
7 | M/79 | Facial nerve schwannoma | 17 | 2 | Yes | No biopsy‡ | Stable disease | 28 | AWD |
28 | 6 | Progressive, irreversible | Regular follow-up | ||||||
8 | F/56 | Facial nerve schwannoma | 180 | 3 | Yes | No biopsy‡ | Stable Disease | 24 | AWD |
180 | 6 | Progressive, irreversible | Regular follow-up | ||||||
9 | F/59 | Parotid malignant tumor | 23 | 3 | Yes | Contralateral neck node biopsy | 4 | AWD until last follow-up | |
34 | 6 | Progressive, irreversible | Recommend surgery and postoperative radiation therapy |