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Table 3 Dominant and recessive hereditary models

From: Glucocorticoid receptor (NR3C1) genetic polymorphisms and the outcomes of sudden sensorineural hearing loss

SNP

Overall, n (%)

P value1

Adjusted OR (95% CI)2

P value3

Poor

Good

rs12653301

Genotypes

GG

31 (33)

34 (34)

0.922

1.004

 

AG + AA

62 (67)

66 (66)

 

0.97 (0.53–1.77)

0.927

GG + AG

73 (78)

80 (80)

0.797

1.004

 

AA

20 (22)

20 (20)

 

0.91 (0.45–1.84)

0.799

rs17100289

Genotypes

AA

28 (30)

37 (37)

0.311

1.004

 

AT + TT

65 (70)

63 (63)

 

0.73 (0.39–1.33)

0.301

AA + AT

82 (88)

73 (73)

0.008*

1.004

 

TT

11 (12)

27 (27)

 

2.76 (1.31–6.17)

0.007*

rs4912650

Genotypes

TT

36 (39)

40 (40)

0.855

1.004

 

GT + GG

57 (61)

60 (60)

 

0.95 (0.53–1.69)

0.854

TT + GT

78 (84)

86 (86)

0.679

1.004

 

GG

15 (16)

14 (14)

 

0.85 (0.381.87)

0.678

rs4912912

Genotypes

TT

24 (26)

36 (36)

0.126

1.004

 

CT + CC

69 (74)

64 (64)

 

0.62 (0.33–1.14)

0.124

TT + CT

77 (83)

74 (74)

0.134

1.004

 

CC

16 (17)

26 (26)

 

1.70 (0.85–3.49)

0.134

rs6877893

Genotypes

AA

54 (58)

57 (57)

0.881

1.004

 

AG + GG

39 (42)

43 (43)

 

1.04 (0.59–1.85)

0.882

AA + AG

85 (91)

91 (91)

0.922

1.004

 

GG

8 (9)

9 (9)

 

1.05 (0.38–2.92)

0.923

rs9324924

Genotypes

GG

32 (34)

32 (31)

0.723

1.004

 

GT + TT

61 (66)

68 (68)

 

1.12 (0.61–2.05)

0.715

GG + GT

81 (87)

86 (86)

0.823

1.004

 

TT

12 (13)

14 (14)

 

1.10 (0.48–2.59)

0.816

  1. 1χ2 test
  2. 2Adjusted for age and sex
  3. 3Logistic regression
  4. 4Reference group
  5. *P < 0.05