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Table 2 Impact of biomarkers on mortality

From: Prognostic stratification of oropharyngeal cancer patients in a betel nut chewing and low HPV area

Variable

Total

Event (%)

Hazard ratio

P value

p16 status

   

0.006

 p16 negative

91

49 (53.8)

Ref.

 

 p16 positive

25

5 (20.0)

0.274

 

PD-L1

   

0.237

 CPS < 20

71

31 (43.7)

Ref.

 

 CPS ≥ 20

45

23 (51.1)

1.386

 

p53 mutant

   

0.429

 No

94

42 (44.7)

Ref.

 

 Yes

22

12 (54.5)

1.296

 

High EGFR expression

   

0.028

 No (H-score < 200)

82

34 (41.5)

Ref.

 

 Yes (H-score ≥ 200)

34

20 (58.8)

1.86

 
  1. CPS Combined positive score, EGFR Epidermal growth factor receptor, PD-L1 programmed cell death ligand 1