Table 3 Hazard ratios for 5-year overall survival
From: Prognostic stratification of oropharyngeal cancer patients in a betel nut chewing and low HPV area
Variable | HR (95% CI) | P value |
|---|---|---|
Age | 1.03 (1.001–1.06) | 0.042 |
Male | 2.75 (0.86–8.84) | 0.089 |
P16 positive | 0.27 (0.11–0.69) | 0.006 |
PD-L1 | 1.31 (0.76–2.25) | 0.329 |
P53 mutant | 1.30 (0.68–2.45) | 0.429 |
High EGFR expression | 1.86 (1.07–3.24) | 0.028 |
Tumor subsite | ||
Tonsil | Ref. | |
Soft palate | 1.36 (0.70–2.67) | 0.367 |
Others | 1.67 (0.87–3.20) | 0.121 |
Differentiation-poorly | 1.40 (0.78–2.51) | 0.258 |
Treatment | ||
Operation | Ref. | |
CCRT/RT | 1.4 (0.77–2.54) | 0.27 |
IC-based treatment | 0.96 (0.45–2.04) | 0.909 |
cT4 | 3 (1.7–5.29) | < 0.001 |
cN2-N3 | 1.50 (0.88–2.57) | 0.137 |
cStage: III–IV | 1.54 (0.90–2.64) | 0.117 |
Extranodal extension | 1.85 (1.04–3.28) | 0.035 |
Alcohol | 2.17 (1.06–4.44) | 0.034 |
Betel nuts | 1.40 (0.74–2.66) | 0.304 |
Cigarettes | 2.06 (1.09–3.92) | 0.027 |