Fig. 4

Respiratory nasal mucosa of CRS and healthy control mice. Hematoxylin and eosin stain at ×40 magnification of the nasal respiratory mucosa is presented in A Healthy Control and B CRS mice after ovalbumin/protease induction. In the CRS mice, the epithelium is hyperplastic with increased thickness of the lamina propria observed. Increased eosinophils and degranulation are also seen in the subepithelial layer in CRS mice compared to healthy controls