Articles

Correlation between clinical and MRI assessment of depth of invasion in oral tongue squamous cell carcinoma

Neck metastasis is the most important prognostic factor in oral cavity squamous cell carcinomas (SCC). Apart from the T- stage, depth of invasion has been used as a highly predictable factor for microscopic ne...

Authors: H. A. Alsaffar, D. P. Goldstein, E. V. King, J. R. de Almeida, D. H. Brown, R. W. Gilbert, P J. Gullane, O. Espin-Garcia, W. Xu and J. C. Irish

One-and-a-half nostril endoscopic transsphenoidal approach for pituitary adenomas—a technical report

Binostril endoscopic transsphenoidal approach (BETA) provides sufficient manipulation space and wide endoscopic vision, although it increases the trauma of nose. Mononostril endoscopic transsphenoidal approach...

Authors: Guodao Wen, Chao Tang, Chunyu Zhong, Junyang Li, Zixiang Cong, Yuan Zhou, Kaidong Liu, Yong Zhang, Mamatemin Tohti and Chiyuan Ma

Impact of laryngopharyngeal reflux on subjective and objective voice assessments: a prospective study

Laryngopharyngeal reflux is a prevalent, not well-understood disease affecting a high proportion of patients who seek laryngology consultation. The objective of this prospective case series is to explore the s...

Authors: Jérôme R. Lechien, Kathy Huet, Mohamad Khalife, Anne-Françoise Fourneau, Véronique Delvaux, Myriam Piccaluga, Bernard Harmegnies and Sven Saussez

Harmonic scalpel impact on blood loss and operating time in major head and neck surgery: a randomized clinical trial

Long operating time and high blood loss contribute to post-surgical morbidity. Therefore, strategies to reduce these factors should to be tested using robust methods.

Authors: Dieter K. Fritz, T. Wayne Matthews, Shamir P. Chandarana, Steven C. Nakoneshny and Joseph C. Dort

Decision aid prototype development for parents considering adenotonsillectomy for their children with sleep disordered breathing

To describe the process involved in developing a decision aid prototype for parents considering adenotonsillectomy for their children with sleep disordered breathing.

Authors: Erin Maguire, Paul Hong, Krista Ritchie, Jeremy Meier, Karen Archibald and Jill Chorney

Efficacy and mechanism of mandibular advancement devices for persistent sleep apnea after surgery: a prospective study

To explore the feasibility, the efficacy, and the mechanism of mandibular advancement devices (MAD) in the treatment of persistent sleep apnea after surgery.

Authors: Huiping Luo, Xulan Tang, Yuanping Xiong, Lili Meng, Hongliang Yi and Shankai Yin

Practice patterns among thyroid cancer surgeons: implications of performing a prophylactic central neck dissection

Indications for performing a prophylactic central neck dissection (pCND) in papillary thyroid cancer (PTC) remain controversial. It is unclear how identification of lymph node (LN) metastases should impact the...

Authors: Michael W. Deutschmann, Laura Chin-Lenn, Steven C. Nakoneshny, Joseph C. Dort, Janice L. Pasieka and Shamir P. Chandarana

Investigation of EZH2 pathways for novel epigenetic treatment strategies in oropharyngeal cancer

In recent decades, the incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been rising worldwide as a result of increasing oncogenic human papillomavirus (HPV) infections in the oropharynx. EZH2 is ...

Authors: Sherif Idris, Cameron Lindsay, Morris Kostiuk, Colin Andrews, David W. J. Côté, Daniel A. O’Connell, Jeffrey Harris, Hadi Seikaly and Vincent L. Biron

Ectopic parathyroid adenoma in the soft palate: a case report

Ectopic parathyroid adenomas can occur in numerous anatomic locations. While ectopic parathyroid adenomas can rarely occur in the pharyngeal region, this has not previously been described in the soft palate.

Authors: Brent A. Chang, Anil Sharma and Donald W. Anderson

Chylothorax in thyroid surgery: a very rare case and systematic review of the literature

Chylothorax is a very rare but major complication in thyroid surgery and should be apparent to clinicians in this field.

Authors: Verena Merki, Juliane Pichler, Roland Giger and Georgios Mantokoudis

The role of repeat fine needle aspiration in the management of indeterminate thyroid nodules

Management decisions are not straightforward when the Ultrasound Guided Fine Needle Aspiration (USFNA) demonstrates a Bethesda score of either category III or IV, and a diagnostic hemi-thyroidectomy or a repea...

Authors: Alborz Jooya, Joe Saliba, Audrey Blackburn, Michael Tamilia, Michael P. Hier, Alex Mlynarek, Véronique-Isabelle Forest, Louise Rochon, Anca Florea, Hangjun Wang and Richard J. Payne

Survival outcomes in patients with oropharyngeal cancer treated with carboplatin/paclitaxel and concurrent radiotherapy

A commonly employed treatment for advanced staged oropharyngeal squamous cell carcinoma (OPSCC) is concurrent radiation and chemotherapy with cisplatin as the gold standard. Carboplatin is reported to have the...

Authors: M. Roskies, E. Kay-Rivest, M. A. Mascarella, K. Sultanem, A. Mlynarek and M. Hier

A program evaluation of Kids2Hear, a student-run hearing screening program for school children

Hearing deficits in children are demonstrably negatively associated with language acquisition and cognition. Although universal neonatal hearing screening exists, it is not offered equally across Canada. Addit...

Authors: Tina Hu, Katherine Stead, Terence Fu and Blake Papsin

The effect of adenoid hypertrophy on maxillofacial development: an objective photographic analysis

Deformity in the dental arc and facial skeleton by adenoid hypertrophy due to chronic mouth breathing is a well-known process. Most of the related studies have been based on cephalometric analyses. The aim of ...

Authors: Cigdem Fırat Koca, Tamer Erdem and Tuba Bayındır

Targeted next-generation sequencing of TP53 in oral tongue carcinoma from non-smokers

Little is known regarding the etiology and genomic underpinnings of Oral Tongue Squamous Cell Carcinoma (OTSCC) in patients who lack traditional risk factors, yet the incidence is increasing. In particular, th...

Authors: Daniel L. Faden, Sarah T. Arron, Chase M. Heaton, Joseph DeRisi, Andrew P. South and Steven J. Wang

Mental practice in postgraduate training: a randomized controlled trial in mastoidectomy skills

Mental practice, the cognitive rehearsal of a task in the absence of overt physical movement, has been successfully used in teaching complex psychomotor tasks including sports and music, and recently, surgical...

Authors: Anne Conlin, Jane Lea, Manohar Bance, Neil Chadha, Shaun Kilty, Frederick Kozak, Julian Savage, Ravindar Sidhu, Joseph Chen and Brian D. Westerberg

Preliminary cross-sectional reliability and validity of the Skull Base Inventory (SBI) quality of life questionnaire

The Skull Base Inventory (SBI) was developed to assess the quality of life of patients undergoing endoscopic or open approaches for anterior and central skull base pathologies. In this study, we sought to esta...

Authors: Soroush Larjani, Eric Monteiro, Ian Witterick, Allan Vescan, Gelareh Zadeh, Fred Gentili, David P. Goldstein and John R. de Almeida

Middle ear ventilation status postoperatively after translabyrinthine resection of vestibular schwannoma with mastoid obliteration and Eustachian tube occlusion: is the Eustachian tube enough to ventilate the middle ear without the mastoid air cell system?

Gas pressure balance is essential for maintaining normal middle ear function. The mucosal surfaces of the middle ear, the mastoid air cell system (MACS), and the Eustachian tube (ET) play a critical role in th...

Authors: James Belyea, Brandon Wickens and Manohar Bance

Trends in CPAP adherence over twenty years of data collection: a flattened curve

Obstructive sleep apnea (OSA) is a common disorder, and continuous airway positive pressure (CPAP) is considered to be the gold standard of therapy. CPAP however is known to have problems with adherence, with ...

Authors: Brian W. Rotenberg, Dorian Murariu and Kenny P. Pang

Comparison of survival between radiation therapy and trans-oral laser microsurgery for early glottic cancer patients; a retrospective cohort study

The literature reports various treatment methodologies, such as trans-oral laser microsurgery, radiation therapy, total/partial laryngectomies, and concurrent radiation chemotherapy for patients with early lar...

Authors: R. J. De Santis, I. Poon, J. Lee, I. Karam, D. J. Enepekides and K. M. Higgins

Management algorithm for failed gastric pull up reconstruction of laryngopharyngectomy defects: case report and review of the literature

Gastric pull up remains a popular reconstructive option for pharyngoesophagectomy defects extending to thoracic inlet. Gastric necrosis is a dreaded complication of gastric pull up reconstruction and few studi...

Authors: Oleksandr Butskiy, Donald W. Anderson and Eitan Prisman

Heat and moisture exchanger use reduces in-hospital complications following total laryngectomy: a case–control study

Total laryngectomy (TL) is an appropriate oncologic operation for many patients with laryngeal cancer delivering excellent oncologic outcomes, however it remains beset with significant functional consequences....

Authors: A. Foreman, R. J. De Santis, F. Sultanov, D. J. Enepekides and K. M. Higgins

Evaluation of the otolith function using c/oVEMPs in patients with Ménière’s disease

Cervical and ocular vestibular evoked myogenic potentials (c/oVEMPs) reflect otolith function. Up-to-date, there are no published reports on the systemic evaluation of otolith function in Ménière’s Disease (MD...

Authors: Liang Chen, Hui Xu, Wu-qing Wang, Qing-quan Zhang, Qiao-ying Lv and Xi-cheng Song

Vestibular function following unilateral cochlear implantation for profound sensorineural hearing loss

Many Canadians are affected by sensorineural hearing loss (SNHL) and those with severe or profound hearing loss may have poor hearing function despite optimized hearing aids. Cochlear implants (CI) offer effec...

Authors: Gavin J. le Nobel, Euna Hwang, Adrian Wu, Sharon Cushing and Vincent Y. Lin

Interpretation of sonotubometric data based on phase-shift detection

Sonotubometry is a non-invasive means of assessing Eustachian tube (ET) function. Its interpretation remains a complex task with questionable results due to wide variation between trials. A study was conducted...

Authors: Yaw Amoako-Tuffour, Philip Garland and Manohar Bance

Exploring the psychological morbidity of waiting for sinus surgery using a mixed methods approach

Patients with chronic rhinosinusitis (CRS) often have to endure significant wait times for endoscopic sinus surgery (ESS). The pyschiatric impact of placement on a waitlist for ESS has not been explored.

Authors: Gordon Fung-Zak Tsang, Carmen L. McKnight, Laura Minhui Kim and John M. Lee

The use of a modified abbé island flap to reconstruct primary lip defects of over 80 %

Lip reconstruction for defects greater than 80 % present a challenge in maintaining acceptable oral function and good aesthetic results. Abbé flaps offer an excellent reconstructive option but are limited to d...

Authors: Sabin Filimon, Keith Richardson, Michael P. Hier, Michael Roskies and Alex M. Mlynarek

A retrospective review in the management of T3 laryngeal squamous cell carcinoma: an expanding indication for transoral laser microsurgery

The purpose of this study was to evaluate the functional and oncological outcomes of patients treated for T3 laryngeal squamous cell carcinoma. Specifically comparing transoral laser microsurgery and radiother...

Authors: A. Butler, M. H. Rigby, J. Scott, J. Trites, R. Hart and S. M. Taylor

Monoscopic photogrammetry to obtain 3D models by a mobile device: a method for making facial prostheses

The aim of this study is to present the development of a new technique to obtain 3D models using photogrammetry by a mobile device and free software, as a method for making digital facial impressions of patien...

Authors: Rodrigo Salazar-Gamarra, Rosemary Seelaus, Jorge Vicente Lopes da Silva, Airton Moreira da Silva and Luciano Lauria Dib

Clinicopathological features and treatment outcomes of the rare, salivary duct carcinoma of parotid gland

Salivary ductal carcinoma (SDC) of parotid gland is a rare and aggressive entity; accounting for 1–3 % of all malignant salivary gland tumors, 0.2 % of epithelial salivary gland neoplasms, 0.5 % of salivary gl...

Authors: Khalid Hussain AL-Qahtani, Mutahir A. Tunio, Yasser Bayoumi, Venkada Manickam Gurusamy, Fahad Ahmed A. Bahamdain and Hanadi Fatani

Can preoperative thyroglobulin antibody levels be used as a marker for well differentiated thyroid cancer?

It has been reported that thyroglobulin antibody are more frequently elevated in patients with thyroid cancercompared to general population. This study aims at evaluating whether preoperative thyroglobulin ant...

Authors: S. Hosseini, R. J. Payne, F. Zawawi, A. Mlynarek, M. P. Hier, M. Tamilia and V. I. Forest

MRI and CBCT image registration of temporomandibular joint: a systematic review

The purpose of the present review is to systematically and critically analyze the available literature regarding the importance, applicability, and practicality of (MRI), computerized tomography (CT) or cone-b...

Authors: Mohammed A. Q. Al-Saleh, Noura A. Alsufyani, Humam Saltaji, Jacob L. Jaremko and Paul W. Major

The McGill Thyroid Nodule Score’s (MTNS+) role in the investigation of thyroid nodules with benign ultrasound guided fine needle aspiration biopsies: a retrospective review

Ultrasound guided fine needle aspiration (USFNA) biopsies of thyroid nodules sometimes create a decision-making dilemma for surgeons as they may yield falsely benign results. The McGill Thyroid Nodule Score + ...

Authors: Sarah Khalife, Sarah Bouhabel, Veronique-Isabelle Forest, Michael P. Hier, Louise Rochon, Michael Tamilia and Richard J. Payne

The role of transoral robotic surgery, transoral laser microsurgery, and lingual tonsillectomy in the identification of head and neck squamous cell carcinoma of unknown primary origin: a systematic review

Squamous cell carcinoma of the head and neck can present as a cervical metastasis from an unknown primary site. Recently, transoral robotic surgery (TORS) and transoral laser microsurgery (TLM) have been incor...

Authors: Terence S. Fu, Andrew Foreman, David P. Goldstein and John R. de Almeida

Using a nasoseptal flap for the reconstruction of osteoradionecrosis in nasopharyngeal carcinoma: a case report

Osteoradionecrosis (ORN) is a challenging complication in patients with postirradiated nasopharyngeal carcinoma (NPC). The aim of this study was to evaluate the usage of a nasoseptal flap (NSF) after endoscopi...

Authors: Mohamad Adel and Kai-Ping Chang

In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model

Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer with poor overall survival. New therapeutic strategies that target specific molecular lesions driving advanced disease are needed. Herein w...

Authors: Shannon F. Rudy, J. Chad Brenner, Jennifer L. Harris, Jun Liu, Jianwei Che, Megan V. Scott, John Henry Owen, Christine M. Komarck, Martin P. Graham, Emily L. Bellile, Carol R. Bradford, Mark EP Prince and Thomas E. Carey

Avoiding allogenic blood transfusions in endoscopic angiofibroma surgery

Surgical approaches for many tumours are often limited by blood loss, exposure and risk to vital anatomical structures. Therefore, the standard of care for certain skull base tumours has become endoscopic tran...

Authors: Hisham Wasl, Jessica McGuire and Darlene Lubbe

An outcomes analysis of anterior epistaxis management in the emergency department

Many treatment options exist for the management of anterior epistaxis. However, little is known about treatment outcomes. The objective was to identify the currently utilised methods of management and outcomes...

Authors: E. Newton, A. Lasso, W. Petrcich and S. J. Kilty

Reconsidering first-line treatment for obstructive sleep apnea: a systematic review of the literature

Continuous positive airway pressure (CPAP) is typically recommended as first line therapy for obstructive sleep apnea, but the adherence rate of CPAP is problematic. This study’s objective was to systematicall...

Authors: Brian W. Rotenberg, Claudio Vicini, Edward B. Pang and Kenny P. Pang

The surgical plane for lingual tonsillectomy: an anatomic study

The presence of a plane between the lingual tonsils and the underlying soft tissue has not been confirmed. The objective of this study is to ascertain the presence and the characteristics about this plane for ...

Authors: Eugene L. Son, Michael P. Underbrink, Suimin Qiu and Vicente A. Resto

Rinne test: does the tuning fork position affect the sound amplitude at the ear?

Guidelines and text-book descriptions of the Rinne test advise orienting the tuning fork tines in parallel with the longitudinal axis of the external auditory canal (EAC), presumably to maximise the amplitude ...

Authors: Oleksandr Butskiy, Denny Ng, Murray Hodgson and Desmond A. Nunez

Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer

Head and neck cancer is often managed with a combination of surgery, radiation therapy, and chemotherapy, and skin toxicity is not uncommon. Xanthogranuloma is a pathological finding resulting from an inflamma...

Authors: Lisa Singer, Sarah M. Calkins, Andrew E. Horvai, William R. Ryan and Sue S. Yom

Correction of severe columella and tip retraction in silicone implanted Asian short noses

Silicone Implants and other alloplastic materials are frequently used in rhinoplasty to augment Asian short noses. However, nasal deformities as a result of implant-related infections are increasing in inciden...

Authors: Serkan Sertel, Ioana Irina Venara-Vulpe and Philippe Pasche

How can the audiogram be more useful?

The Canadian Hearing and Auditory Research Translation (CHART) group is a newly formed taskforce to develop collaborative research initiatives. Initial discussions centered on diagnostic improvements for middl...

Authors: Robert V Harrison

Oral corticosteroid prescribing habits of Canadian Otolaryngologist-Head and Neck Surgeons

Oral corticosteroids (OCSs) are widely prescribed in Otolaryngology-Head & Neck surgery (OtoHNS). There is evidence in the literature regarding specific dosing regimens. However, it is not known to what extent...

Authors: Saad Ansari, Brian W. Rotenberg and Leigh J. Sowerby

Decisional conflict in patients considering diagnostic thyroidectomy with indeterminate fine needle aspirate cytopathology

Fine needle aspiration (FNA) cytopathology is the gold standard work-up for thyroid nodules. However, indeterminate lesions are encountered commonly and can lead to difficult treatment decisions. We sought to ...

Authors: Benjamin A. Taylor, Robert D. Hart, Matthew H. Rigby, Jonathan Trites, S. Mark Taylor and Paul Hong

Erratum to: Detection of bacteria in middle ear effusions based on the presence of allergy: does allergy augment bacterial infection in the middle ear?

Authors: Woo Jin Kim, Byung-Guk Kim, Ki-Hong Chang and Jeong-Hoon Oh

Informed consent: do information pamphlets improve post-operative risk-recall in patients undergoing total thyroidectomy: prospective randomized control study

Informed consent consists of basic five elements: voluntarism, capacity, disclosure, understanding, and ultimate decision-making. Physician disclosure, patient understanding, and information retention are all ...

Authors: Hussain Alsaffar, Lindsay Wilson, Dev P. Kamdar, Faizullo Sultanov, Danny Enepekides and Kevin M. Higgins

Balloon dilation of the eustachian tube: a tympanometric outcomes analysis

Eustachian tube dysfunction (ETD) is a common medical issue, occurring in at least 1 % of the adult population. Patients suffering from ET dysfunction typically present with complaints of hearing loss or sensa...

Authors: Blair Williams, Benjamin A. Taylor, Neil Clifton and Manohar Bance

Evaluation of the utricular and saccular function using oVEMPs and cVEMPs in BPPV patients

It is well-known that ocular vestibular evoked myogenic potentials (oVEMPs) predominantly reflect utricular function whilst cervical vestibular evoked myogenic potentials (cVEMPs) reflect saccular function. To...

Authors: Hui Xu, Fa-ya Liang, Liang Chen, Xi-cheng Song, Michael Chi Fai Tong, Jiun Fong Thong, Qing-quan Zhang and Yan Sun