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  1. To review the available evidence and make recommendations regarding use of systemically administered drugs in combination or in sequence with radiation (RT) and/or surgery for cure and/or organ preservation in...

    Authors: Eric Winquist, Chika Agbassi, Brandon M. Meyers, John Yoo and Kelvin K. W. Chan

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:29

    Content type: Review

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  2. In otologic surgery good visualization is paramount, and patients with bleeding diatheses or who need to be anti-coagulated can present a significant challenge. Here, we determine whether Floseal™, a hemostati...

    Authors: Carol Nhan, Aren Bezdjian, Abdullah Alarfaj and Sam J. Daniel

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:24

    Content type: Original research article

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  3. This study sheds important light on the association between sino-nasal symptoms and global quality of life in patients with chronic rhinosinusitis waiting for endoscopic sinus surgery. Using patient-reported i...

    Authors: Bassem M. N. Hanna, R. Trafford Crump, Guiping Liu, Jason M. Sutherland and Arif S. Janjua

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:23

    Content type: Original research article

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  4. Thyroid incidentaloma is defined as an unsuspected thyroid lesion found on imaging study or while performing a surgery non-related to the thyroid gland. Most recent scientific literature tends to demonstrate a...

    Authors: N. Hagenimana, J. Dallaire, É. Vallée and M. Belzile

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:22

    Content type: Original research article

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  5. FoxP3 is the most dependable marker for regulatory T cells which play a major role in immune tolerance. Foxp3 gene polymorphisms were associated with various autoimmune diseases and clearance of viral infectio...

    Authors: Tack-Kyun Kwon, Eun Jae Chung, Nuri Lee, Eun Youn Roh and Eun Young Song

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:21

    Content type: Short report

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  6. The resection of large oropharyngeal tumors traditionally involves a lip-splitting mandibulotomy for adequate margin visualization and free flap reconstruction of the surgical defect. Transoral robotic surgery...

    Authors: Vincent L. Biron, Daniel A. O’Connell, Brittany Barber, Jessica M. Clark, Colin Andrews, Caroline C. Jeffery, David W. J. Côté, Jeffrey Harris and Hadi Seikaly

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:20

    Content type: Original research article

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  7. Cochlear Duct Length (CDL) has been an important measure for the development and advancement of cochlear implants. Emerging literature has shown CDL can be used in preoperative settings to select the proper si...

    Authors: Robert W. Koch, Hanif M. Ladak, Mai Elfarnawany and Sumit K. Agrawal

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:19

    Content type: Review

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  8. Autoimmune inner ear disease (AIED) is a rare condition characterized by bilateral fluctuating sensorineural hearing loss (SNHL). The labile nature of this hearing loss makes it difficult to accurately quantif...

    Authors: Scott Kohlert and Matthew Bromwich

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:18

    Content type: Original research article

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  9. Thyroid metastases to distant sites are uncommon incidents, most often metastasizing to the lungs and bones. Rates of metastasis to the kidney are particularly low, ranging from 2.8–3.8% for papillary and 6–20...

    Authors: Jin Soo Andy Song, S. Mark Taylor, Jonathan Trites, Matthew H. Rigby, Martin Joseph Bullock, Jennifer Merrimen, Ricardo Rendon and Robert D. Hart

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:17

    Content type: Case report

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  10. The residency match is an important event in an aspiring physician’s career. Otolaryngology – Head and Neck Surgery (OTL-HNS) is a surgical specialty that has enjoyed high numbers of applicants to its residenc...

    Authors: E. Kay-Rivest, N. Varma, G. M. Scott, J. J. Manoukian, M. Desrosiers, J. P. Vaccani and L. H. P. Nguyen

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:16

    Content type: Original research article

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  11. HPV infection causes cervical cancer, mediated in part by the degradation of Scribble via the HPV E6 oncoprotein. Recently, Scribble has been shown to be an important regulator of the Hippo signaling cascade. ...

    Authors: Faisal Alzahrani, Leanne Clattenburg, Shanmugam Muruganandan, Martin Bullock, Kaitlyn MacIsaac, Michael Wigerius, Blair A. Williams, M. Elise R. Graham, Matthew H. Rigby, Jonathan R. B. Trites, S. Mark Taylor, Christopher J. Sinal, James P. Fawcett and Robert D. Hart

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:15

    Content type: Original research article

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  12. Medialization thyroplasty and injection laryngoplasty are widely accepted treatment options for unilateral vocal fold paralysis. Although both procedures result in similar clinical outcomes, little is known ab...

    Authors: Samantha Tam, Hongmei Sun, Sisira Sarma, Jennifer Siu, Kevin Fung and Leigh Sowerby

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:14

    Content type: Original research article

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  13. Otolaryngology-Head and Neck surgery resident physicians (OHNSR) have a high prevalence of burnout, job dissatisfaction and stress as shown within the literature. Formal mentorship programs (FMP) have a proven...

    Authors: Han Zhang, Andre Isaac, Erin D. Wright, Yaser Alrajhi and Hadi Seikaly

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:13

    Content type: Original research article

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  14. Adenotonsillectomy is the most commonly performed operation for pediatric snoring/sleep disordered breathing (S/SDB). However, 20–40% of patients will fail to improve. Drug-induced sleep endoscopy (DISE) may p...

    Authors: Malak Jamal Gazzaz, André Isaac, Scott Anderson, Noura Alsufyani, Yaser Alrajhi and Hamdy El-Hakim

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:12

    Content type: Original research article

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  15. Human papilloma virus (HPV) has been implicated in the development of a large proportion of oropharyngeal squamous cell carcinoma (OPSCC). Current techniques used to diagnose HPV etiology require histopatholog...

    Authors: Natasha Cohen, Michael Gupta, Lilian Doerwald-Munoz, Dan Jang, James Edward Massey Young, Stuart Archibald, Bernard Jackson, Jenny Lee and Max Chernesky

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:11

    Content type: Original research article

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  16. The objective of this study was to validate our approach of treating primary hyperparathyroidism using sestamibi scan directed parathyroidectomy, without routine use of intraoperative parathyroid hormone measu...

    Authors: Alexandra Thielmann and Paul Kerr

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:10

    Content type: Original research article

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  17. Epigenetic modifications are heritable changes in gene expression that do not directly alter DNA sequence. These modifications include DNA methylation, histone post-translational modifications, small and non-c...

    Authors: Cameron Lindsay, Hadi Seikaly and Vincent L. Biron

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:9

    Content type: Review

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  18. The midline and paramedian mandibulotomy are surgical procedures that divide the mandibular bone into two halves and disconnects the condylar heads of the TMJ from each other. This study aimed to prospectively...

    Authors: Mohammed A. Q. Al-Saleh, Kumaradevan Punithakumar, Manuel Lagravere, Pierre Boulanger, Jacob L. Jaremko, John Wolfaardt, Paul W. Major and Hadi Seikaly

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:8

    Content type: Original research article

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  19. Bacteria are suspected players in the pathogenesis of chronic rhinosinusitis (CRS), yet their exact role is not understood. We investigated the effect of planktonic and biofilm of staphylococcus aureus (SA) an...

    Authors: Almoaidbellah Rammal, Marc Tewfik and Simon Rousseau

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:7

    Content type: Original research article

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  20. Passive transcutaneous osseointegrated hearing implant systems have become increasingly popular more recently. The area over the implant is vulnerable due to vibration and pressure from the externally worn sou...

    Authors: Adam Perenyi, Zsofia Bere, Janos Jarabin, Balazs Sztano, Edit Kukla, Ziad Bikhazi, Laszlo Tiszlavicz, Ferenc Toth, Jozsef Geza Kiss and Laszlo Rovo

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:6

    Content type: Original research article

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  21. The incidence of oropharyngeal squamous cell carcinoma (OPSCC) caused by oncogenic human papillomavirus (HPV) is rising worldwide. HPV-OPSCC is commonly diagnosed by RT-qPCR of HPV E6 and E7 oncoproteins or by...

    Authors: Andre Isaac, Morris Kostiuk, Han Zhang, Cameron Lindsay, Fawaz Makki, Daniel A. O’Connell, Jeffrey R. Harris, David W. J. Cote, Hadi Seikaly and Vincent L. Biron

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:5

    Content type: Original research article

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  22. We report an unusual case of a 66-year-old female with a suspicious thoracic outlet mass presenting with severe biochemical hyperparathyroidism and classic hypercalcemic symptoms of renal and bone involvement.

    Authors: Joanne Kim, Gilad Horowitz, Michael Hong, Mario Orsini, Sylvia L. Asa and Kevin Higgins

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:4

    Content type: Case report

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  23. Human papillomavirus (HPV) is an important cause of head and neck squamous cell carcinoma (HNSCC), especially in young people. These tumours overexpress p16 and respond well to treatment. The rapid detection o...

    Authors: Jason K. Wasserman, Ryan Rourke, Bibianna Purgina, Lisa Caulley, Jim Dimitroulakis, Martin Corsten and Stephanie Johnson-Obaseki

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:3

    Content type: Original research article

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    The Correction to this article has been published in Journal of Otolaryngology - Head & Neck Surgery 2018 47:49

  25. Bell´s palsy is the most common cause of facial paralysis worldwide and the most common disorder of the cranial nerves. It is a diagnosis of exclusion, accounting for 60–75% of all acquired peripheral facial n...

    Authors: S. K. Mueller, H. Iro, M. Lell, F. Seifert, C. Bohr, C. Scherl, A. Agaimy and M. Traxdorf

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:1

    Content type: Case report

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  26. The conventional technique for cancer resection margin analysis studies only 0.1% of the surgical margins. Complete frozen section margins - also known as Mohs margins – allows for analysis of 100% of the surg...

    Authors: Mathieu Bergeron, Pierre Gauthier and Nathalie Audet

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:63

    Content type: Original research article

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  27. The majority of chemoradiation (CRT) trials for locally advanced head and neck squamous cell carcinoma (HNSCC) have relied on platinum-based chemotherapy regimens administered every-3-weeks. However, given the...

    Authors: James M. Melotek, Benjamin T. Cooper, Matthew Koshy, Joshua S. Silverman and Michael T. Spiotto

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:62

    Content type: Original research article

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  28. Neck metastasis is the most important prognostic factor in oral cavity squamous cell carcinomas (SCC). Apart from the T- stage, depth of invasion has been used as a highly predictable factor for microscopic ne...

    Authors: H. A. Alsaffar, D. P. Goldstein, E. V. King, J. R. de Almeida, D. H. Brown, R. W. Gilbert, P J. Gullane, O. Espin-Garcia, W. Xu and J. C. Irish

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:61

    Content type: Original research article

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  29. Binostril endoscopic transsphenoidal approach (BETA) provides sufficient manipulation space and wide endoscopic vision, although it increases the trauma of nose. Mononostril endoscopic transsphenoidal approach...

    Authors: Guodao Wen, Chao Tang, Chunyu Zhong, Junyang Li, Zixiang Cong, Yuan Zhou, Kaidong Liu, Yong Zhang, Mamatemin Tohti and Chiyuan Ma

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:60

    Content type: Original research article

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  30. Laryngopharyngeal reflux is a prevalent, not well-understood disease affecting a high proportion of patients who seek laryngology consultation. The objective of this prospective case series is to explore the s...

    Authors: Jérôme R. Lechien, Kathy Huet, Mohamad Khalife, Anne-Françoise Fourneau, Véronique Delvaux, Myriam Piccaluga, Bernard Harmegnies and Sven Saussez

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:59

    Content type: Original research article

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  31. Long operating time and high blood loss contribute to post-surgical morbidity. Therefore, strategies to reduce these factors should to be tested using robust methods.

    Authors: Dieter K. Fritz, T. Wayne Matthews, Shamir P. Chandarana, Steven C. Nakoneshny and Joseph C. Dort

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:58

    Content type: Original research article

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  32. To describe the process involved in developing a decision aid prototype for parents considering adenotonsillectomy for their children with sleep disordered breathing.

    Authors: Erin Maguire, Paul Hong, Krista Ritchie, Jeremy Meier, Karen Archibald and Jill Chorney

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:57

    Content type: Original research article

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  33. To explore the feasibility, the efficacy, and the mechanism of mandibular advancement devices (MAD) in the treatment of persistent sleep apnea after surgery.

    Authors: Huiping Luo, Xulan Tang, Yuanping Xiong, Lili Meng, Hongliang Yi and Shankai Yin

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:56

    Content type: Original research article

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  34. Indications for performing a prophylactic central neck dissection (pCND) in papillary thyroid cancer (PTC) remain controversial. It is unclear how identification of lymph node (LN) metastases should impact the...

    Authors: Michael W. Deutschmann, Laura Chin-Lenn, Steven C. Nakoneshny, Joseph C. Dort, Janice L. Pasieka and Shamir P. Chandarana

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:55

    Content type: Original research article

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  35. In recent decades, the incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been rising worldwide as a result of increasing oncogenic human papillomavirus (HPV) infections in the oropharynx. EZH2 is ...

    Authors: Sherif Idris, Cameron Lindsay, Morris Kostiuk, Colin Andrews, David W. J. Côté, Daniel A. O’Connell, Jeffrey Harris, Hadi Seikaly and Vincent L. Biron

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:54

    Content type: Original research article

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  36. Ectopic parathyroid adenomas can occur in numerous anatomic locations. While ectopic parathyroid adenomas can rarely occur in the pharyngeal region, this has not previously been described in the soft palate.

    Authors: Brent A. Chang, Anil Sharma and Donald W. Anderson

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:53

    Content type: Case report

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  38. Management decisions are not straightforward when the Ultrasound Guided Fine Needle Aspiration (USFNA) demonstrates a Bethesda score of either category III or IV, and a diagnostic hemi-thyroidectomy or a repea...

    Authors: Alborz Jooya, Joe Saliba, Audrey Blackburn, Michael Tamilia, Michael P. Hier, Alex Mlynarek, Véronique-Isabelle Forest, Louise Rochon, Anca Florea, Hangjun Wang and Richard J. Payne

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:51

    Content type: Original research article

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  39. A commonly employed treatment for advanced staged oropharyngeal squamous cell carcinoma (OPSCC) is concurrent radiation and chemotherapy with cisplatin as the gold standard. Carboplatin is reported to have the...

    Authors: M. Roskies, E. Kay-Rivest, M. A. Mascarella, K. Sultanem, A. Mlynarek and M. Hier

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:50

    Content type: Original research article

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  40. Hearing deficits in children are demonstrably negatively associated with language acquisition and cognition. Although universal neonatal hearing screening exists, it is not offered equally across Canada. Addit...

    Authors: Tina Hu, Katherine Stead, Terence Fu and Blake Papsin

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:49

    Content type: Short report

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  41. Deformity in the dental arc and facial skeleton by adenoid hypertrophy due to chronic mouth breathing is a well-known process. Most of the related studies have been based on cephalometric analyses. The aim of ...

    Authors: Cigdem Fırat Koca, Tamer Erdem and Tuba Bayındır

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:48

    Content type: Original research article

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  42. Little is known regarding the etiology and genomic underpinnings of Oral Tongue Squamous Cell Carcinoma (OTSCC) in patients who lack traditional risk factors, yet the incidence is increasing. In particular, th...

    Authors: Daniel L. Faden, Sarah T. Arron, Chase M. Heaton, Joseph DeRisi, Andrew P. South and Steven J. Wang

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:47

    Content type: Short report

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  43. Mental practice, the cognitive rehearsal of a task in the absence of overt physical movement, has been successfully used in teaching complex psychomotor tasks including sports and music, and recently, surgical...

    Authors: Anne Conlin, Jane Lea, Manohar Bance, Neil Chadha, Shaun Kilty, Frederick Kozak, Julian Savage, Ravindar Sidhu, Joseph Chen and Brian D. Westerberg

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:46

    Content type: Original research article

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  44. The Skull Base Inventory (SBI) was developed to assess the quality of life of patients undergoing endoscopic or open approaches for anterior and central skull base pathologies. In this study, we sought to esta...

    Authors: Soroush Larjani, Eric Monteiro, Ian Witterick, Allan Vescan, Gelareh Zadeh, Fred Gentili, David P. Goldstein and John R. de Almeida

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:45

    Content type: Original research article

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  45. Gas pressure balance is essential for maintaining normal middle ear function. The mucosal surfaces of the middle ear, the mastoid air cell system (MACS), and the Eustachian tube (ET) play a critical role in th...

    Authors: James Belyea, Brandon Wickens and Manohar Bance

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:44

    Content type: Original research article

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  46. Obstructive sleep apnea (OSA) is a common disorder, and continuous airway positive pressure (CPAP) is considered to be the gold standard of therapy. CPAP however is known to have problems with adherence, with ...

    Authors: Brian W. Rotenberg, Dorian Murariu and Kenny P. Pang

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:43

    Content type: Original research article

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  47. The literature reports various treatment methodologies, such as trans-oral laser microsurgery, radiation therapy, total/partial laryngectomies, and concurrent radiation chemotherapy for patients with early lar...

    Authors: R. J. De Santis, I. Poon, J. Lee, I. Karam, D. J. Enepekides and K. M. Higgins

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:42

    Content type: Original research article

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  48. Gastric pull up remains a popular reconstructive option for pharyngoesophagectomy defects extending to thoracic inlet. Gastric necrosis is a dreaded complication of gastric pull up reconstruction and few studi...

    Authors: Oleksandr Butskiy, Donald W. Anderson and Eitan Prisman

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:41

    Content type: Case report

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  49. Total laryngectomy (TL) is an appropriate oncologic operation for many patients with laryngeal cancer delivering excellent oncologic outcomes, however it remains beset with significant functional consequences....

    Authors: A. Foreman, R. J. De Santis, F. Sultanov, D. J. Enepekides and K. M. Higgins

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:40

    Content type: Original research article

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  50. Cervical and ocular vestibular evoked myogenic potentials (c/oVEMPs) reflect otolith function. Up-to-date, there are no published reports on the systemic evaluation of otolith function in Ménière’s Disease (MD...

    Authors: Liang Chen, Hui Xu, Wu-qing Wang, Qing-quan Zhang, Qiao-ying Lv and Xi-cheng Song

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2016 45:39

    Content type: Original research article

    Published on:

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ISSN: 1916-0216

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