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  1. Human papillomavirus (HPV) has been identified as an etiopathogenetic factor in oropharyngeal squamous cell carcinoma. The HPV E6 and E7 oncogenes are instrumental in promoting proliferation and blocking differen...

    Authors: Robert E. Brown, Syed Naqvi, Mary F. McGuire, Jamie Buryanek and Ron J. Karni

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:52

    Content type: Original research article

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  2. Although 20–40% of primary care complaints are Otolaryngology-Head and Neck Surgery (OtoHNS) related, little emphasis is placed on OtoHNS instruction at the undergraduate medical education level. An OtoHNS cle...

    Authors: Grace Margaret Scott, Corliss Ann Elizabeth Best and Damian Christopher Micomonaco

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:51

    Content type: Original research article

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  3. Only few therapeutic options exist for patients with refractory sudden idiopathic sensorineural hearing loss (SISHL). Little is known about the efficacy of second-line therapies. Rheopheresis seems to be an ef...

    Authors: Milan Kostal, Jakub Drsata, Milan Bláha, Miriam Lánská and Viktor Chrobok

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:50

    Content type: Original research article

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  4. We have identified a cause of falsely elevated parathyroid hormone (PTH) levels after total parathyroidectomy with forearm auto-transplantation (TPT-ATx). Our cases highlight the need to draw PTH samples remot...

    Authors: Diana Khalil and Paul D. Kerr

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:49

    Content type: Case report

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  5. Tympanoplasty is a common procedure performed by Otolaryngologists. Many types of autologous grafts have been used with variations of techniques with varying results. This is the first systematic review of the...

    Authors: Caroline C. Jeffery, Cameron Shillington, Colin Andrews and Allan Ho

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:48

    Content type: Review

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  6. Eustachian tube (ET) dysfunction can be very difficult to diagnose accurately. Our aim is to determine whether a newly developed sonotubometric test using clicks can reliably detect ET opening during swallowin...

    Authors: Justin M. Pyne, Yaw Amoako-Tuffour, Guy Earle, Graham McIntyre, Michael B. Butler and Manohar Bance

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:47

    Content type: Original research article

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  7. Minimally Invasive Ponto Surgery (MIPS) was recently described as a new technique to facilitate the placement of percutaneous bone anchored hearing devices.

    Authors: Yaeesh Sardiwalla, Nicholas Jufas and David P. Morris

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:46

    Content type: Original research article

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  8. Head and neck cancer of unknown primary (HNCUP) is rare and prospective studies are lacking. The impact of different prognostic factors such as age and N stage is not completely known, the optimal treatment is...

    Authors: Lars Axelsson, Jan Nyman, Hedda Haugen-Cange, Mogens Bove, Leif Johansson, Shahin De Lara, Anikó Kovács and Eva Hammerlid

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:45

    Content type: Original research article

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  9. Vestibular disorders have been reported following cochlear implant (CI) surgery, but the literature shows a wide discrepancy in the reported clinical impact. The aim of this meta-analysis is to quantify the ef...

    Authors: Iman Ibrahim, Sabrina Daniela da Silva, Bernard Segal and Anthony Zeitouni

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:44

    Content type: Review

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  10. Practice variability exists for the extent of neck dissection undertaken for papillary thyroid carcinoma (PTC) metastatic to the lateral neck nodes, with disagreement over routine level V dissection.

    Authors: Jason J. Xu, Eugene Yu, Caitlin McMullen, Jesse Pasternak, Jim Brierley, Richard Tsang, Han Zhang, Antoine Eskander, Lorne Rotstein, Anna M. Sawka, Ralph Gilbert, Jonathan Irish, Patrick Gullane, Dale Brown, John R. de Almeida and David P. Goldstein

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:43

    Content type: Original research article

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  11. Learners often utilize online resources to supplement formalized curricula, and to appropriately support learning, these resources should be of high quality. Thus, the objectives of this study are to develop ...

    Authors: Nathan Yang, Sarah Hosseini, Marco A. Mascarella, Meredith Young, Nancy Posel, Kevin Fung and Lily H. P. Nguyen

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:42

    Content type: Original research article

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  12. Noise-induced hearing loss is one of the most common forms of sensorineural hearing loss, is a major health problem, is largely preventable and is probably more widespread than revealed by conventional pure to...

    Authors: Trung N. Le, Louise V. Straatman, Jane Lea and Brian Westerberg

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:41

    Content type: Review

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  13. The inserted cochlear implanted electrode is covered at the site of the round window or cochleostomy to prevent infections and leakage. In a surgically hearing preservational concept, low intracochlear pressur...

    Authors: Ingo Todt, Julica Utca, Dania Karimi, Arne Ernst and Philipp Mittmann

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:40

    Content type: Original research article

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  14. We aim to characterize the workup received by and identify any delays to diagnosis or treatment in patients referred to a tertiary cancer centre with the diagnosis of squamous cell carcinoma in neck node(s) an...

    Authors: Kevin Martell, Joanna Mackenzie, Warren Kerney and Harold Yeehau Lau

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:39

    Content type: Original research article

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  15. This was a diagnostic accuracy study to develop an algorithm based on administrative database codes that identifies patients with Chronic Rhinosinusitis (CRS) who have endoscopic sinus surgery (ESS).

    Authors: Kristian I. Macdonald, Shaun J. Kilty and Carl van Walraven

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:38

    Content type: Original research article

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  16. Adenotonsillectomy (AT) is the most commonly performed procedure for sleep disordered breathing (SDB) in pediatrics. However, 20-40% of patients will have persistent signs and symptoms of SDB after AT. Drug-in...

    Authors: Noura Alsufyani, Andre Isaac, Manisha Witmans, Paul Major and Hamdy El-Hakim

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:37

    Content type: Original research article

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  17. Eosinophilic chronic frontal sinusitis is difficult to treat compared with non-eosinophilic sinusitis because of recurring inflammation and polyp formation in the frontal recess after the post-operative follow...

    Authors: Kazunori Kubota, Sachio Takeno, Takayuki Taruya, Atsushi Sasaki, Takashi Ishino and Katsuhiro Hirakawa

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:36

    Content type: Original research article

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  19. Research productivity is an important component of the CanMEDS Scholar role and is an accreditation requirement of Canadian Otolaryngology training programs. Our objective was to determine if an association ex...

    Authors: Scott Kohlert, Laura Zuccaro, Laurie McLean and Kristian Macdonald

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:34

    Content type: Original research article

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  20. Autologous and synthetic nasal and auricular frameworks require skin coverage. The surgeon’s decides on the appropriate skin coverage for reconstruction based on colour matching, subcutaneous tissue thickness,...

    Authors: M. F. Griffin, B. C. Leung, Y. Premakumar, M. Szarko and P. E. Butler

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:33

    Content type: Original research article

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  21. Hypertrophy of the lingual tonsil tissue in the adult patient is thought to contribute to the pathophysiology of obstructive sleep apnea. The underlying etiology of lingual tonsil hypertrophy (LTH) in the adul...

    Authors: Matthew S. Harris, Brian W. Rotenberg, Kathryn Roth and Leigh J. Sowerby

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:32

    Content type: Original research article

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  22. The surgical excision of anatomic obstructions such as adenoids, palatine or lingual tonsils are commonly performed in children with sleep disordered breathing (SDB). Imaging studies measuring airway changes p...

    Authors: Noura A. Alsufyani, Michelle L. Noga, Manisha Witmans, Irene Cheng, Hamdy El-Hakim and Paul W. Major

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:31

    Content type: Original research article

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  23. Plate-related complications following head and neck cancer ablation and reconstruction remains a challenging problem often requiring further management and reconstructive surgeries. We aim to identify an assoc...

    Authors: Christopher M. Yao, Hedyeh Ziai, Gordon Tsang, Andrea Copeland, Dale Brown, Jonathan C. Irish, Ralph W. Gilbert, David P. Goldstein, Patrick J. Gullane and John R. de Almeida

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:30

    Content type: Original research article

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  24. To review the available evidence and make recommendations regarding use of systemically administered drugs in combination or in sequence with radiation (RT) and/or surgery for cure and/or organ preservation in...

    Authors: Eric Winquist, Chika Agbassi, Brandon M. Meyers, John Yoo and Kelvin K. W. Chan

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:29

    Content type: Review

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  25. The incidence of thyroid nodules is increasing among patients in North America. Few of these nodules harbour malignancy, thus further research is required to identify predictive markers of malignant thyroid di...

    Authors: Mark Sasson, Emily Kay-Rivest, Rami Shoukrun, Anca Florea, Michael Hier, Veronique-Isabelle Forest, Michael Tamilia and Richard J. Payne

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:28

    Content type: Original research article

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  26. Sudden sensorineural hearing loss (SSHL) is a disease, which severely affects the patient’s social and relational life. The underlying pathomechanisms have not been finally clarified yet and outcome is not pre...

    Authors: Daniel Weiss, Armin Julius Böcker, Mario Koopmann, Eleftherios Savvas, Matthias Borowski and Claudia Rudack

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:27

    Content type: Original research article

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  28. Thyroid nodules are common and often benign, although prove to be malignant upon surgical pathology in 5–15% of cases. When assessed with ultrasound-guided fine-needle aspiration (USFNA), 15–30% of the nodules...

    Authors: Emily Kay-Rivest, Jamie Tibbo, Sarah Bouhabel, Michael Tamilia, Rebecca Leboeuf, Veronique-Isabelle Forest, Michael P. Hier, Loren Savoury and Richard J. Payne

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:25

    Content type: Original research article

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  29. In otologic surgery good visualization is paramount, and patients with bleeding diatheses or who need to be anti-coagulated can present a significant challenge. Here, we determine whether Floseal™, a hemostati...

    Authors: Carol Nhan, Aren Bezdjian, Abdullah Alarfaj and Sam J. Daniel

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:24

    Content type: Original research article

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  30. This study sheds important light on the association between sino-nasal symptoms and global quality of life in patients with chronic rhinosinusitis waiting for endoscopic sinus surgery. Using patient-reported i...

    Authors: Bassem M. N. Hanna, R. Trafford Crump, Guiping Liu, Jason M. Sutherland and Arif S. Janjua

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:23

    Content type: Original research article

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  31. Thyroid incidentaloma is defined as an unsuspected thyroid lesion found on imaging study or while performing a surgery non-related to the thyroid gland. Most recent scientific literature tends to demonstrate a...

    Authors: N. Hagenimana, J. Dallaire, É. Vallée and M. Belzile

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:22

    Content type: Original research article

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  32. FoxP3 is the most dependable marker for regulatory T cells which play a major role in immune tolerance. Foxp3 gene polymorphisms were associated with various autoimmune diseases and clearance of viral infectio...

    Authors: Tack-Kyun Kwon, Eun Jae Chung, Nuri Lee, Eun Youn Roh and Eun Young Song

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:21

    Content type: Short report

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  33. The resection of large oropharyngeal tumors traditionally involves a lip-splitting mandibulotomy for adequate margin visualization and free flap reconstruction of the surgical defect. Transoral robotic surgery...

    Authors: Vincent L. Biron, Daniel A. O’Connell, Brittany Barber, Jessica M. Clark, Colin Andrews, Caroline C. Jeffery, David W. J. Côté, Jeffrey Harris and Hadi Seikaly

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:20

    Content type: Original research article

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  34. Cochlear Duct Length (CDL) has been an important measure for the development and advancement of cochlear implants. Emerging literature has shown CDL can be used in preoperative settings to select the proper si...

    Authors: Robert W. Koch, Hanif M. Ladak, Mai Elfarnawany and Sumit K. Agrawal

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:19

    Content type: Review

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  35. Autoimmune inner ear disease (AIED) is a rare condition characterized by bilateral fluctuating sensorineural hearing loss (SNHL). The labile nature of this hearing loss makes it difficult to accurately quantif...

    Authors: Scott Kohlert and Matthew Bromwich

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:18

    Content type: Original research article

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  36. Thyroid metastases to distant sites are uncommon incidents, most often metastasizing to the lungs and bones. Rates of metastasis to the kidney are particularly low, ranging from 2.8–3.8% for papillary and 6–20...

    Authors: Jin Soo Andy Song, S. Mark Taylor, Jonathan Trites, Matthew H. Rigby, Martin Joseph Bullock, Jennifer Merrimen, Ricardo Rendon and Robert D. Hart

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:17

    Content type: Case report

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  37. The residency match is an important event in an aspiring physician’s career. Otolaryngology – Head and Neck Surgery (OTL-HNS) is a surgical specialty that has enjoyed high numbers of applicants to its residenc...

    Authors: E. Kay-Rivest, N. Varma, G. M. Scott, J. J. Manoukian, M. Desrosiers, J. P. Vaccani and L. H. P. Nguyen

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:16

    Content type: Original research article

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  38. HPV infection causes cervical cancer, mediated in part by the degradation of Scribble via the HPV E6 oncoprotein. Recently, Scribble has been shown to be an important regulator of the Hippo signaling cascade. ...

    Authors: Faisal Alzahrani, Leanne Clattenburg, Shanmugam Muruganandan, Martin Bullock, Kaitlyn MacIsaac, Michael Wigerius, Blair A. Williams, M. Elise R. Graham, Matthew H. Rigby, Jonathan R. B. Trites, S. Mark Taylor, Christopher J. Sinal, James P. Fawcett and Robert D. Hart

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:15

    Content type: Original research article

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  39. Medialization thyroplasty and injection laryngoplasty are widely accepted treatment options for unilateral vocal fold paralysis. Although both procedures result in similar clinical outcomes, little is known ab...

    Authors: Samantha Tam, Hongmei Sun, Sisira Sarma, Jennifer Siu, Kevin Fung and Leigh Sowerby

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:14

    Content type: Original research article

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  40. Otolaryngology-Head and Neck surgery resident physicians (OHNSR) have a high prevalence of burnout, job dissatisfaction and stress as shown within the literature. Formal mentorship programs (FMP) have a proven...

    Authors: Han Zhang, Andre Isaac, Erin D. Wright, Yaser Alrajhi and Hadi Seikaly

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:13

    Content type: Original research article

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  41. Adenotonsillectomy is the most commonly performed operation for pediatric snoring/sleep disordered breathing (S/SDB). However, 20–40% of patients will fail to improve. Drug-induced sleep endoscopy (DISE) may p...

    Authors: Malak Jamal Gazzaz, André Isaac, Scott Anderson, Noura Alsufyani, Yaser Alrajhi and Hamdy El-Hakim

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:12

    Content type: Original research article

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  42. Human papilloma virus (HPV) has been implicated in the development of a large proportion of oropharyngeal squamous cell carcinoma (OPSCC). Current techniques used to diagnose HPV etiology require histopatholog...

    Authors: Natasha Cohen, Michael Gupta, Lilian Doerwald-Munoz, Dan Jang, James Edward Massey Young, Stuart Archibald, Bernard Jackson, Jenny Lee and Max Chernesky

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:11

    Content type: Original research article

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  43. The objective of this study was to validate our approach of treating primary hyperparathyroidism using sestamibi scan directed parathyroidectomy, without routine use of intraoperative parathyroid hormone measu...

    Authors: Alexandra Thielmann and Paul Kerr

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:10

    Content type: Original research article

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  44. Epigenetic modifications are heritable changes in gene expression that do not directly alter DNA sequence. These modifications include DNA methylation, histone post-translational modifications, small and non-c...

    Authors: Cameron Lindsay, Hadi Seikaly and Vincent L. Biron

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:9

    Content type: Review

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  45. The midline and paramedian mandibulotomy are surgical procedures that divide the mandibular bone into two halves and disconnects the condylar heads of the TMJ from each other. This study aimed to prospectively...

    Authors: Mohammed A. Q. Al-Saleh, Kumaradevan Punithakumar, Manuel Lagravere, Pierre Boulanger, Jacob L. Jaremko, John Wolfaardt, Paul W. Major and Hadi Seikaly

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:8

    Content type: Original research article

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  46. Bacteria are suspected players in the pathogenesis of chronic rhinosinusitis (CRS), yet their exact role is not understood. We investigated the effect of planktonic and biofilm of staphylococcus aureus (SA) an...

    Authors: Almoaidbellah Rammal, Marc Tewfik and Simon Rousseau

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:7

    Content type: Original research article

    Published on:

  47. Passive transcutaneous osseointegrated hearing implant systems have become increasingly popular more recently. The area over the implant is vulnerable due to vibration and pressure from the externally worn sou...

    Authors: Adam Perenyi, Zsofia Bere, Janos Jarabin, Balazs Sztano, Edit Kukla, Ziad Bikhazi, Laszlo Tiszlavicz, Ferenc Toth, Jozsef Geza Kiss and Laszlo Rovo

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:6

    Content type: Original research article

    Published on:

  48. The incidence of oropharyngeal squamous cell carcinoma (OPSCC) caused by oncogenic human papillomavirus (HPV) is rising worldwide. HPV-OPSCC is commonly diagnosed by RT-qPCR of HPV E6 and E7 oncoproteins or by...

    Authors: Andre Isaac, Morris Kostiuk, Han Zhang, Cameron Lindsay, Fawaz Makki, Daniel A. O’Connell, Jeffrey R. Harris, David W. J. Cote, Hadi Seikaly and Vincent L. Biron

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:5

    Content type: Original research article

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  49. We report an unusual case of a 66-year-old female with a suspicious thoracic outlet mass presenting with severe biochemical hyperparathyroidism and classic hypercalcemic symptoms of renal and bone involvement.

    Authors: Joanne Kim, Gilad Horowitz, Michael Hong, Mario Orsini, Sylvia L. Asa and Kevin Higgins

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:4

    Content type: Case report

    Published on:

  50. Human papillomavirus (HPV) is an important cause of head and neck squamous cell carcinoma (HNSCC), especially in young people. These tumours overexpress p16 and respond well to treatment. The rapid detection o...

    Authors: Jason K. Wasserman, Ryan Rourke, Bibianna Purgina, Lisa Caulley, Jim Dimitroulakis, Martin Corsten and Stephanie Johnson-Obaseki

    Citation: Journal of Otolaryngology - Head & Neck Surgery 2017 46:3

    Content type: Original research article

    Published on:

    The Correction to this article has been published in Journal of Otolaryngology - Head & Neck Surgery 2018 47:49

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Journal of Otolaryngology - Head & Neck Surgery

ISSN: 1916-0216

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