Figure 1
From: Cyclin D1 overexpression is associated with poor prognosis in oropharyngeal cancer
Examples of a case from Group 1 (favourable outcome group; upper panel, A, B, C) and a case from Group 2 (adverse outcome group; lower panel, D, E, F). A (diffuse punctate signals) and D (negative) showing CISH staining of HPV-HR DNA; B (diffuse strong cytoplasmic staining and nuclear staining) and E (negative) showing IHC staining of p16 protein; C (negative) and F (diffuse strong nuclear staining) showing IHC staining of cyclin D1. (Original magnification 100×).