Articles

Molecular mutations as a possible factor for determining extent of thyroid surgery

Molecular testing of thyroid nodules is a diagnostic tool used to better understand the nature of thyroid nodules. The aim of this study is to better comprehend the relationship between specific mutations and ...

Authors: Joshua R. Krasner, Nourah Alyouha, Marc Pusztaszeri, Veronique-Isabelle Forest, Michael P. Hier, Galit Avior and Richard J. Payne

Intra-operative nasal compression after lateral osteotomy to minimize post-operative Peri-orbital ecchymosis and edema

Post-operative periorbital ecchymosis and edema following rhinoplasty is a well-known sequela of surgery. Unfortunately, this can be a source of distress for patients, resulting in a longer post-operative reco...

Authors: L. Sowerby, L. M. Kim, W. Chow and C. Moore

The infectious thyroid nodule: a case report of mucormycosis associated with ibrutinib therapy

Acute invasive fungal infections of the head and neck secondary to tyrosine kinase inhibitors are rare and potentially life-threatening events.

Authors: Marco A. Mascarella, Lorne Schweitzer, Mahmoud Alreefi, Jennifer Silver, Derin Caglar, Vivian G. Loo, Keith Richardson, Philippe Dufresne, Todd C. Lee and Nader Sadeghi

Prospective pilot study of Floseal® for the treatment of anterior epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT)

Epistaxis is the most common symptom of hereditary hemorrhagic telangiectasia (HHT), affecting more than 98% of adults with HHT, with significant impact on quality of life. Floseal® has been shown to be effect...

Authors: John M. Lee, Vincent Wu, Marie E. Faughnan, Andrea Lasso, Andrea Figol and Shaun J. Kilty

Supraglottic p16+ squamous cell carcinoma during pregnancy: a case report and review of the literature

Head and neck cancer during pregnancy is uncommon. Specifically, laryngeal cancer in pregnancy has only been previously reported 10 times. HPV p16+ supraglottic cancer during pregnancy has never been described...

Authors: Jakob Pugi, Marc Levin and Michael Gupta

Electrophysiological measurements with electrode types of different perimodiolar properties and the same cochlear implant electronics – a retrospective comparison study

Authors: A. Perenyi, F. Toth, B. Dimak, R. Nagy, P. Schoerg, J. Jori, J. G. Kiss, G. Sprinzl, M. Csanady and L. Rovo

Topical biomaterials to prevent post-tonsillectomy hemorrhage

Despite advances in surgical technique, postoperative hemorrhage remains a common cause of mortality and morbidity for patients following tonsillectomy. Application of biomaterials at the time of tonsillectomy...

Authors: Lumei Liu, Cole Rodman, Noah E. Worobetz, Jed Johnson, Charles Elmaraghy and Tendy Chiang

Systematic review and meta-analysis of T1 glottic cancer outcomes comparing CO₂ transoral laser microsurgery and radiotherapy

The objective of this study is to compare the oncologic outcomes of CO₂ transoral laser microsurgery (TLM) and radiotherapy (RT) for treatment of T1 glottic carcinoma.

Authors: Michael F. Vaculik, Colin A. MacKay, S. Mark Taylor, Johnathan R. B. Trites, Robert D. Hart and Matthew H. Rigby

Survival outcomes of marijuana users in p16 positive oropharynx cancer patients

Oropharynx squamous cell carcinoma (OPSCC) has become the predominant subsite for head and neck mucosal cancers (HNC) due to the rise of human papillomavirus (HPV) related disease. Previous studies have sugges...

Authors: Han Zhang, Michael Xie, Marc Levin, Stuart D. Archibald, B. Stanley Jackson, J. E. M. Young and Michael K. Gupta

Clinical implications of Delphian lymph node metastasis in papillary thyroid carcinoma: a single-institution study, systemic review and meta-analysis

To evaluate the possible predictive value and clinicopathological characteristics of Delphian lymph node metastasis in papillary thyroid carcinoma.

Authors: Bin Wang, Xing-zhu Wen, Wei Zhang and Ming Qiu

Utility of clinical features with fine needle aspiration biopsy for diagnosis of Warthin tumor

Conservative management of Warthin tumor (WT) may be a viable alternative to surgery, but there are concerns of missed malignancies on fine needle aspiration biopsy (FNAB). The purpose of this study is to meas...

Authors: Thomas So, Axel Sahovaler, Anthony Nichols, Kevin Fung, John Yoo, Michele M. Weir and S. Danielle MacNeil

Prevalence and aggressiveness of papillary thyroid carcinoma in surgically-treated graves’ disease patients: a retrospective matched cohort study

Reported rates of thyroid cancer in Graves’ disease (GD) vary widely. The aim of this study was to evaluate the prevalence of papillary thyroid carcinoma (PTC), including aggressive forms, in GD compared to ma...

Authors: Eunice You, Marco A. Mascarella, Abrar Al Jassim, Veronique-Isabelle Forest, Michael P. Hier, Michael Tamilia, Marc Pusztaszeri and Richard J. Payne

Evaluating short and long term outcomes following pediatric Myringoplasty with Gelfoam graft for tympanic membrane perforation following ventilation tube insertion

Myringotomy with ventilation tube (VT) insertion to treat recurrent acute otitis media and chronic secretory otitis media has become one of the most common surgical procedures performed in children. Although c...

Authors: Jin Soo Song, Gerard Corsten and Liane B. Johnson

Voice hoarseness in a patient with underlying Eisenmenger’s syndrome: a case report

The natural history of patients diagnosed with Eisenmenger’s Syndrome typically revolve around the pediatric population. Medical advances have allowed these patients to live longer and present with a different...

Authors: Palak Suryavanshi, Sreejit Parameswaran, Nishant Sharma, Russell A. Murphy and Anil R. Sharma

A case report of a primary lymphoma of the tongue presenting as trigeminal neuralgia

Primary lymphoma of the oral cavity is a rare phenomenon. Herein we describe a unique presentation of lymphoma of the tongue which initially manifested as trigeminal neuralgia.

Authors: Andrew J. Arifin, Selay Lam and S. Danielle MacNeil

Evaluation of one-point fixation for zygomaticomaxillary complex fractures using a three-dimensional photogrammetric analysis

The goal of treatment for zygomaticomaxillary (ZM) complex (ZMC) fractures is to achieve stability and restore aesthetic appearance through three-dimensional reduction and rigid fixation. The purpose of this s...

Authors: Se Young Kim, Seung Min Nam, Eun Soo Park and Yong Bae Kim

The middle fossa approach with self-drilling screws: a novel technique for BONEBRIDGE implantation

Bone conduction implants can be used in the treatment of conductive or mixed hearing loss. The BONEBRIDGE bone conduction implant (BB-BCI) is an active, transcutaneous device. BB-BCI implantation can be perfor...

Authors: Peng You, Lauren H. Siegel, Zahra Kassam, Matthew Hebb, Lorne Parnes, Hanif M. Ladak and Sumit Kishore Agrawal

Impact of metformin on disease control and survival in patients with head and neck cancer: a retrospective cohort study

A number of in vitro and clinical studies have suggested potential antineoplastic effects of metformin. The impact of this medication on outcomes in head and neck cancer is less clear. Our aim was to determine...

Authors: Daniel J. Lee, Caitlin P. McMullen, Andrew Foreman, Shao Hui Huang, Lin Lu, Wei Xu, John R. de Almeida, Geoffrey Liu, Scott V. Bratman and David P. Goldstein

The effect of second hand smoke in patients with squamous cell carcinoma of the head and neck

Active tobacco smoking is a well-known risk factor for head and neck malignancy, and strong evidence has associated tobacco as the main carcinogenic factor in squamous cell cancers of this region. Evidence sup...

Authors: Sherif Idris, Abdulsalam Baqays, André Isaac, Jason K. M. Chau, Karen H. Calhoun and Hadi Seikaly

An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature

Central giant cell granulomas are benign tumours of the mandible, presenting in children and young adults. Divided into non- and aggressive subtypes, the aggressive subtype is relatively rare and can occasiona...

Authors: Yiqiao Wang, Andre Le, Dina El Demellawy, Mary Shago, Michael Odell and Stephanie Johnson-Obaseki

Correction to: Clinically relevant phenotypes in chronic rhinosinusitis

Following publication of the original article [1], the authors reported an error in Table 1. In the second columns of the ‘Radiology’ row, ‘Normal anterolateral sinus mucosa’ should read ‘Normal superolateral ...

Authors: Jessica W. Grayson, Marina Cavada and Richard J. Harvey

Endoscopic removal of ectopic sinonasal teeth: a systematic review

Ectopic sinonasal teeth are uncommon. The classic approach to removal of such foreign bodies was the Caldwell-Luc. In recent years however, endoscopic approaches have become increasingly utilized. Despite this...

Authors: Marc Levin and Doron D. Sommer

Opioid prescribing practices following elective surgery in Otolaryngology-Head & Neck Surgery

Prescription opioid abuse has become a major issue across the world and especially in North America. Canada has the second highest number of opioid prescriptions per capita in the world, second only to the Uni...

Authors: Mathew Biskup, Agnieszka Dzioba, Leigh J. Sowerby, Eric Monteiro and Julie Strychowsky

Perceptions and observations of shared decision making during pediatric otolaryngology surgical consultations

Increased parental involvement in the decision-making process when considering elective surgeries for their children, termed shared decision-making (SDM), may lead to positive outcomes. The objective of this s...

Authors: Yolanda Evong, Jill Chorney, Gilanders Ungar and Paul Hong

Oncological and functional outcomes following transoral laser microsurgery in patients with T2a vs T2b glottic squamous cell carcinoma

There is a paucity of evidence comparing oncological and voice outcomes between T2a and T2b glottic squamous cell carcinoma (SCC) patients treated with transoral laser microsurgery (TLM). This study identified...

Authors: David Forner, Matthew H. Rigby, Robert D. Hart, Jonathan R. Trites and S. Mark Taylor

Obstructive sleep apnea in patients with laryngeal cancer after supracricoid or vertical partial laryngectomy

To investigate whether partial laryngectomy is a risk factor for obstructive sleep apnea (OSA) and the effect of different partial laryngectomy methods on OSA.

Authors: Lei Ouyang, Liang Yi, Lin Wang, Qinglai Tang, Xinming Yang and Shisheng Li

Effect of preoperative immunonutrition on complications after salvage surgery in head and neck cancer

Patients undergoing salvage surgery for recurrent head and neck squamous cell carcinoma are at high risk of postoperative complications due to the adverse effects of radiotherapy on wound healing. Malnutrition...

Authors: Simon Andreas Mueller, Catherine Mayer, Beat Bojaxhiu, Carla Aeberhard, Philipp Schuetz, Zeno Stanga and Roland Giger

A pilot study examining Toronto-area family physician perspectives on thyroid neoplasm evaluation

The incidence of thyroid cancer (TC) is known to be very high in the Greater Toronto Area of Ontario, Canada. We performed a pilot survey study examining Toronto-area family physician (FP) perspectives on thyr...

Authors: Arjun Kundra, David P. Goldstein, Kimberly Wintemute, Sangeet Ghai, Richard W. Tsang, Karuna Gupta, Donatus R. Mutasingwa, Jeff Weissberger, Ella Huszti, Patrick Brown, Huan Jiang and Anna M. Sawka

Clinically relevant phenotypes in chronic rhinosinusitis

Chronic rhinosinusitis (CRS) is a complex disease that incorporates many different conditions. Currently, primary CRS is considered a disease of broad airway inflammation, however, the previous classification ...

Authors: Jessica W. Grayson, Marina Cavada and Richard J. Harvey

Subjective and objective vestibular changes that occur following paediatric cochlear implantation: systematic review and meta-analysis

Cochlear implantation can result in post-operative vestibular dysfunction of unknown clinical significance. The objective of this study was to characterize the presence, magnitude, and clinical significance of...

Authors: Michael Yong, Emily Young, Jane Lea, Hannah Foggin, Erica Zaia, Frederick K. Kozak and Brian D. Westerberg

Donor site morbidity following radial forearm free flap reconstruction with split thickness skin grafts using negative pressure wound therapy

Donor site complications secondary to radial forearm free flap (RFFF) reconstruction can limit recovery. Optimizing hand and wrist function in the post-operative period may allow more efficient self-care and r...

Authors: Jessica M. Clark, Shannon Rychlik, Jeffrey Harris, Hadi Seikaly, Vincent L. Biron and Daniel A. O’Connell

French translation, cultural adaptation and validation of the BDDQ-AS for rhinoplasty patients

The Body Dysmorphic Disorder Questionnaire-Aesthetic Surgery (BDDQ-AS) is a validated questionnaire that is used as a screening tool for body dysmorphic disorder (BDD) in aesthetic rhinoplasty patients. The BD...

Authors: Daniel Milad, Marie-Renée Atallah, Youcef-Hamza Benamer, Mikhail Saltychev, Sam P. Most and Sami P. Moubayed

Fellowship training in microvascular surgery and post-fellowship practice patterns: a cross sectional survey of microvascular surgeons from facial plastic and reconstructive surgery programs

There is a lack of published literature on the training in microvascular reconstructive techniques in facial plastic and reconstructive surgery (FPRS) fellowships or of the extent these techniques are continue...

Authors: Douglas M. Bennion, Peter T. Dziegielewski, Brian J. Boyce, Yadro Ducic and Raja Sawhney

The impact of comorbid depression in chronic rhinosinusitis on post-operative sino-nasal quality of life and pain following endoscopic sinus surgery

Depression and chronic pain are debilitating disorders that co-exist with many chronic diseases. Chronic rhinosinusitis (CRS) is no exception. Nonetheless, little is known about the association between these c...

Authors: Javier Ospina, Guiping Liu, Trafford Crump, Jason M. Sutherland and Arif Janjua

Translation, cultural adaptation and validation of the SCHNOS in French

The Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) is a validated questionnaire that assesses functional and aesthetic outcomes of rhinoplasty patients. There are 274 million French speakers w...

Authors: Marie-Renée Atallah, Daniel Milad, Youcef-Hamza Benamer, Mikhail Saltychev, Sam P. Most and Sami P. Moubayed

The role of repeat fine needle aspiration in managing indeterminate thyroid nodules

The Bethesda System is the most widely used for reporting fine needle aspiration (FNA) cytology. It recommends a repeat FNA (rFNA) when initial results are category I or III. It is unclear how often rFNA provi...

Authors: Laura Allen, Ayham Al Afif, Matthew H. Rigby, Martin J. Bullock, Jonathan Trites, S. Mark Taylor and Robert D. Hart

Contemporary decongestant practices of Canadian otolaryngologists for endoscopic sinus surgery

Cocaine has traditionally been the topical decongestant most frequently used for visualization of the surgical field in Endoscopic Sinus Surgery (ESS). Alternatives include xylometazoline, oxymetazoline, and e...

Authors: Jonathan W. Reid, Brian W. Rotenberg and Leigh J Sowerby

Infantile myofibromatosis treated by mandibulectomy and staged reconstruction with submental flap and free fibula flap: a case report

Infantile myofibromatosis is the most common benign fibrous tumor in infants. Three different types have been reported in the literature. The most commonly affected areas are the head, the neck and the trunk. ...

Authors: Alexandra Maby, Benoit Guay and François Thuot

Free versus pedicled flaps for reconstruction of head and neck cancer defects: a systematic review

The present review focuses on comparative studies of reconstruction with free flaps (FF) versus pedicled flaps (PF) after oncologic resection.

Authors: Fanny Gabrysz-Forget, Paul Tabet, Akram Rahal, Eric Bissada, Apostolos Christopoulos and Tareck Ayad

Loop underlay tympanoplasty for anterior, subtotal and total tympanic membrane perforations: a retrospective review

The study aims at reporting our experience with loop underlay tympanoplasty, a modification of the underlay technique previously reported, for the reconstruction of anterior, subtotal or total tympanic membran...

Authors: Rana Barake, Tamer El Natout, Marc Bassim and Mohammad Ali El Natout

A retrospective analysis of two tertiary care dizziness clinics: a multidisciplinary chronic dizziness clinic and an acute dizziness clinic

Vertigo remains a diagnostic challenge for primary care, emergency, and specialist physicians. Multidisciplinary clinics are increasingly being employed to diagnose and manage patients with dizziness. We descr...

Authors: Phillip Staibano, Daniel Lelli and Darren Tse

Managing the airway catastrophe: longitudinal simulation-based curriculum to teach airway management

A longitudinal curriculum was developed in conjunction with anesthesiologists, otolaryngologists, emergency physicians and experts in medical simulation and education.

Authors: Lily H. P. Nguyen, Ilana Bank, Rachel Fisher, Marco Mascarella and Meredith Young

Treatment of oral cancers during pregnancy: a case-based discussion

Malignancies occur in approximately 1:1000 pregnancies; the most common being breast (46%) and hematological (18%) malignancies. Oral cancers account for only 2% of all cancers in pregnant women, and there are...

Authors: Kiyoshi Sato, Hiroaki Shimamoto, Yumi Mochizuki, Hideaki Hirai, Hirofumi Tomioka, Risa Shimizu, Eriko Marukawa, Haruhisa Fukayama, Ryoichi Yoshimura, Hiroo Ishida and Hiroyuki Harada

Teaching communication skills to OTL-HNS residents: multisource feedback and simulated scenarios

Effective communication has been linked to a reduction in adverse events and improved patient compliance. Currently in Otolaryngology – Head and Neck Surgery (OTL-HNS) residency programs, there is limited expl...

Authors: Pier-Luc Beaudoin, Mathilde Labbé, Amanda Fanous, Meredith Young, Jamie Rappaport, Yoon Soo Park, John Manoukian and Lily H. P. Nguyen

Competence of final year otolaryngology residents with the bedside head impulse test

The bedside head impulse test (bHIT) is a clinical method of assessing the vestibulo-ocular reflex (VOR). It is a critical component of the bedside assessment of dizzy patients, and can help differentiate acut...

Authors: D A Lelli, D Tse and J P Vaccani

Perioperative Teaching and Feedback: How are we doing in Canadian OTL-HNS programs?

Discrepancies between resident and faculty perceptions regarding optimal teaching and feedback during surgery are well known but these differences have not yet been described in Otolaryngology - Head and Neck ...

Authors: Z. Chaudhry, M. Campagna-Vaillancourt, M. Husein, R. Varshney, K. Roth, A. Gooi and LHP Nguyen

Dizziness at a Canadian tertiary care hospital: a cost-of-illness study

In the Canadian health care system, determining overall costs associated with a particular diagnostic subgroup of patients, in this case dizzy patients, is the first step in the process of determining where co...

Authors: Andre Le, Daniel A. Lelli, Sasha Van Katwyk, Debora Hogan, Kednapa Thavorn and Darren Tse

A randomized controlled trial to test the efficacy of trans-tympanic injections of a sodium thiosulfate gel to prevent cisplatin-induced ototoxicity in patients with head and neck cancer

Cisplatin-induced hearing loss is frequent and severe. Antioxidants such as sodium thiosulfate (STS) can neutralize the effects of cisplatin. The objective of the trial was to test the efficacy of trans-tympan...

Authors: Viannique Rolland, François Meyer, Matthieu J. Guitton, Richard Bussières, Daniel Philippon, Isabelle Bairati, Mathieu Leclerc and Mathieu Côté

Risk stratification models in human papillomavirus-associated oropharyngeal squamous cell carcinoma: the Nova Scotia distribution

The incidence of oropharyngeal squamous cell carcinoma is increasing with a growing proportion of diagnoses associated with human papillomavirus (p16 + OSCC), which generally confers a favorable prognosis. For...

Authors: David Forner, Matthew H. Rigby, Derek Wilke, S. Mark Taylor and Nathan Lamond

Morphological analysis of sigmoid sinus anatomy: clinical applications to neurotological surgery

The primary objective of this study was to use high-resolution micro-CT images to create accurate three-dimensional (3D) models of several intratemporal structures, and to compare several surgically important ...

Authors: Kylen Van Osch, Daniel Allen, Bradley Gare, Thomas J. Hudson, Hanif Ladak and Sumit K. Agrawal