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Table 4 Frozen and permanent section analyses of different patient subgroups

From: Frozen section analysis and sentinel lymph node biopsy in well differentiated thyroid cancer

Type of analysis

N

sensitivity

95% CI

specificity

95% CI

PPV

95% CI

NPV

95% CI

p-value

FS sum

300

68.8

53.6-80.9

100

98.1-100

100

87.0-100

94.4

90.7-96.7

<0.0001

PS sum

300

89.6

76.6-96.1

100

98.1-100

100

89.8-100

98.1

95.3-99.3

<0.0001

FS, fnac (+)

138

70.7

54.3-83.4

100

95.3-100

100

85.4-100

89.0

81.2-93.9

<0.0001

PS, fnac (+)

138

90.2

75.9-96.8

100

95.3-100

100

88.3-100

96.0

89.6-98.7

<0.0001

FS, fnac (−)

162

57.1

20.2-88.2

100

97.0-100

100

39.6-100

98.1

94.1-99.5

<0.0001

PS, fnac (−)

162

85.7

42.0-99.2

100

97.0-100

100

51.7-100

99.4

95.9-100

<0.0001

  1. FS frozen section, PS permanent section, sum summary analysis, fnac (+), conclusive pre-operative fine-needle aspiration cytology, fnac (−) inconclusive fine-needle aspiration cytology, CI confidence interval, PPV positive predictive value, NPV negative predictive value.