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Table 4 Frozen and permanent section analyses of different patient subgroups

From: Frozen section analysis and sentinel lymph node biopsy in well differentiated thyroid cancer

Type of analysis N sensitivity 95% CI specificity 95% CI PPV 95% CI NPV 95% CI p-value
FS sum 300 68.8 53.6-80.9 100 98.1-100 100 87.0-100 94.4 90.7-96.7 <0.0001
PS sum 300 89.6 76.6-96.1 100 98.1-100 100 89.8-100 98.1 95.3-99.3 <0.0001
FS, fnac (+) 138 70.7 54.3-83.4 100 95.3-100 100 85.4-100 89.0 81.2-93.9 <0.0001
PS, fnac (+) 138 90.2 75.9-96.8 100 95.3-100 100 88.3-100 96.0 89.6-98.7 <0.0001
FS, fnac (−) 162 57.1 20.2-88.2 100 97.0-100 100 39.6-100 98.1 94.1-99.5 <0.0001
PS, fnac (−) 162 85.7 42.0-99.2 100 97.0-100 100 51.7-100 99.4 95.9-100 <0.0001
  1. FS frozen section, PS permanent section, sum summary analysis, fnac (+), conclusive pre-operative fine-needle aspiration cytology, fnac (−) inconclusive fine-needle aspiration cytology, CI confidence interval, PPV positive predictive value, NPV negative predictive value.