Immunoglobulin G4-related diseases in the head and neck: a systematic review

Table 5 Treatment and progress

Treatments Received by Patients (N = 129)		n	%
Surgical Management Alone		15	11.6
Combined Surgical and Medical Management		4	3.1
Medical Management Alone		107	82.9
	Treatment with Corticosteroids^a Alone	84	65.1
	Treatment with Corticosteroids and One Additional Immunosuppressive Agent^b	16	12.4
	Treatment with Corticosteroids and Multiple Additional Immunosuppressive Agents	10	7.8
Treatment Outcomes (N = 99)		n	%
Full Remission with Medical Treatment		89	90.0
Full Remission with Corticosteroids Alone		67	67.7
	Intolerance, Relapse with Taper, or Treatment Failure with Corticosteroids as First Line	32	32.3
Full Remission with Addition of Single Immunosuppressive Agent to Corticosteroids		14	14.1
Full Remission with Addition of Multiple Immunosuppressive Agents to Corticosteroids		8	8.1
Remission Not Achieved		9	9.1

^aCorticosteroids included: prednisolone, methylprednisone and triamcinolone injections
^bAdditional immunosuppressive agents included: rituximab, methotrexate, azathioprine, mycophenolate mofetil, tamoxifen, 6-mercaptopurine, chlorambucil, cyclosporine and cyclopohosphamide

ISSN: 1916-0216