Table 3 Pattern of failure after thyroidectomy and radioactive iodine therapy in children and adults with differentiated thyroid cancer
Failures | Children Age below 18 years (n = 27) | Young adults Age 19–25 years (n = 78) | Adults Age 26–30 years (n =52) | P value |
|---|---|---|---|---|
Locoregional, n (%) | 6 (22.2) | 9 (11.5) | 3 (5.8) | 0.032 |
Thyroid bed | 1 (16.7) | 2 (22.2) | 0 | |
Lymph nodes | 5 (83.3) | 7 (77.8) | 3 (100) | |
Distant, n (%) | 10 (37.0) | 9 (10.3) | 5 (9.6) | 0.002 |
Lungs | 10 (100) | 9 (100) | 4 (80.0) | |
Bones | - | - | 1 (20.0) | |
Locoregional + distant | 4 (14.8) | 4 (5.1) | 2 (3.8) | 0.035 |
10 year LRC rate | 75.3% | 87.3 % | 93.2 % | 0.001 |
10 year DMC rate | 64.7 % | 84.8 % | 94.2 % | 0.0001 |
10 year OS rate | 92.3 % | 96.2 % | 100 % | 0.079 |