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Table 1 Mean Hearing Threshold (dB) Differences from Baseline and day 7 and 30 post Injection

From: Can floseal™ be applied safely during otologic surgery? Assessment of ototoxicity in a chinchilla animal model

 

Day 7

Day 30

Frequency (in kHz)

8

20

25

8

20

25

Experimental (Floseal™)

−8.3 ± 5.3

8.9 ± 3.4

−7.5 ± 3.8

−2.8 ± 3.4

11.1 ± 3.4

−0.3 ± 3.4

Control (PBS)

−7.8 ± 5.1

7.5 ± 4.0

−1.9 ± 5.1

−1.1 ± 3.5

10.8 ± 4.3

−0.8 ± 4.9

  1. dB decibels, kHz kilohertz, PBS phosphate buffered saline
  2. Auditory brainstem response (ABR) threshold shifts in the control and experimental ears at 7 and 30 days post-application of Floseal™