Table 1 Patient, tumor, and treatment data for all patients divided by HPV status
All patients | p16 positive | p16 negative | p-value | |
|---|---|---|---|---|
Subjects, n (%) | 68 | 41a (69) | 18a (31) | |
Age at diagnosis (years) | ||||
Mean (SD) | 59.4 (10.9) | 57.2 (10.2) | 63.4 (11.2) | 0.082 |
Median (range) | 58 (36–87) | 56 (36–85) | 62 (48–85) | |
Gender, male n (%) | 55 (81) | 32 (78) | 16 (89) | 0.55 |
Histology | ||||
SCC | 58 (85) | 37 (90) | 13 (72) | |
SCC poorly diff | 30 (44) | 20 (49) | 9 (47) | |
SCC mod-highly diff | 11 (16) | 6 (15) | 2 (11) | |
SCC not spec | 17 (25) | 11 (27) | 2 (11) | |
Carcinoma not spec | 10 (15) | 4 (10) | 5 (28) | 0.24 |
Extracapsular extension | ||||
Yes | 11 (16) | 7 (23) | 4 (44) | |
No | 30 (44) | 23 (77) | 5 (56) | 0.41 |
N stage | ||||
N1 | 13 (19) | 9 (22) | 1 (6) | |
N2 | 43 (63) | 24 (59) | 14 (78) | |
N2a | 24 (35) | 14 (34) | 10 (56) | |
N2b | 13 (19) | 8 (20) | 2 (11) | |
N2c | 6 (9) | 2 (5) | 2 (11) | |
N3 | 12 (18) | 8 (20) | 3 (17) | 0.76 |
Treatment | ||||
Treatment A | 36 (53) | 28 (68) | 8 (44) | |
Treatment B | 25 (37) | 10 (24) | 6 (33) | |
Treatment C | 7 (10) | 3 (7) | 4 (22) | 0.052 |