Peri-operative factors predisposing to pharyngocutaneous fistula after total laryngectomy: analysis of a large multi-institutional patient cohort

Table 5 Multivariate regression analysis of risk factors for PCF in patients receiving primary closure

Variable	Comparison	Odds Ratio	95% CI	P-value
Age	Increase by 10 years	0.99	0.68–1.43	0.95
Gender	Male vs. female	0.94	0.33–2.70	0.91
BMI	≥ 18.5 vs. < 18.5 kg/m² (underweight)	0.28	0.11–0.73	0.009
Pre-op wound infection	Yes vs. no	5.12	0.88–29.63	0.068
Chronic steroid use	Yes vs. no	3.28	0.89–12.13	0.07
Wound class	Contaminated vs. Clean/Clean-contaminated	3.01	0.56–16.16	0.20
Wound class	Dirty vs Clean/Clean-contaminated	2.50	0.24–26.38	0.44

ISSN: 1916-0216