Table 3 Results for hydrogen peroxide-based antiseptic preparations
From: Systematic review of ototoxic pre-surgical antiseptic preparations – what is the evidence?
Author, Year | Population | Intervention | Control | Outcome |
|---|---|---|---|---|
R. Perez, 2003 [13] | 22 Sand Rats | a) Hydrogen peroxide 3% solution Exposure time 5 days. ABR and VsEP tested on day 8 after initial exposure | a) Saline as negative control b) Gentamicin as positive control | a) ABR could not be tested in 3/12 animals. All remaining animals had elevated base line from 55 dB to 108 dB b) VsEP could not be recorded in 5/12 animals. All remaining animals had a increased from baseline of mean latency time |
ME Nader, 2007 [12] | 18 Chinchillas | Solution tested a) Hydrogen peroxide 3% solution Exposure time 5 min ABR performed 1 day after exposure | Contralateral ear to experimental ear | b) No difference of ABR from baseline recording prior to instillation of hydrogen peroxide. |