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Table 2 Treatment characteristics and outcomes of patients experiencing locoregional recurrence (LRR) or distant metastasis (DM) as first recurrence of adenoid cystic carcinoma

From: Mortality risk after clinical management of recurrent and metastatic adenoid cystic carcinoma

 

LRR (n = 20)

p value

DM (n = 16)

p value

Treatment

 Surgery

10

 

5

 

 Surgery + PORT

8

 

0

 

 RT alone

1

 

4

 

  CF-RT

1

 

0

 

  SBRT

0

 

2

 

  Palliative RT

0

 

2

 

 Systemic therapy alone

1

 

1

 

 Observation

0

 

6

 

3-year PFS

82.1%

 

61.2%

 

3-year PFS

 Low-risk

100%

0.15

80.0%

0.48

 High-risk

64.3%

 

44.4%

 

3-year OS

73.3%

 

85.1%

 

3-year OS

 Low-risk

87.5%

0.01

100%

0.03

 High-risk

62.3%

 

76.2%

 
  1. CF-RT conventionally fractionated radiation therapy, RT radiation therapy, PFS progression-free survival, PORT post-operative radiation therapy, OS overall survival