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Table 10 Preoperative risk factors

From: Free versus pedicled flaps for reconstruction of head and neck cancer defects: a systematic review

 

Article

FF

PF

p-value

Smoking

Gieger, 2016

62.0%

61.8%

0.985

Jing, 2014

4 (18.18%)a

1 (3.70%)a

ND

Granzow, 2013

9 (56%)

13 (72%)

0.5

Mallet, 2009

23 (92%)

43 (98%)

ND

Funk, 2002

13 (61.9%)

18 (85.7%)

0.159

Prior head and neck surgery

Goyal, 2017

189 (32.1%)

122 (58.7%)

< 0.001

Gieger, 2016a

14.0%

30.9%

0.039

Chepeha, 2004

25 (35%)

31 (29%)

ND

Tsue, 1997

5 (17%)

11 (46%)

0.05

Systemic diseases (CVD, HTA, DM)

Fang, 2013

4 (20%)

20 (83.33%)

< 0.001

3 (25%)

< 0.001

COPD

Sinha, 2017

12.2%

15%

0.4538

Mallet, 2009

6 (24%)

10 (22%)

0.96

DM

Sinha, 2017

17.7%

15.8%

0.6900

Granzow, 2013

5 (31%)

0

0.02

Hsing, 2011

2 (33.3%)

4 (66.7%)

0.986

HTA

Gieger, 2016

56.0%

58.2%

0.821

Granzow, 2013

6 (38)

5 (28)

0.7

CAD

Sinha, 2017

15.6%

18.8%

0.4162

Granzow, 2013

1 (6%)

1 (6%)

1.0

Mallet, 2009

6 (24%)

16 (36%)

0.46

DLP

Gieger, 2016

34.0%

34.6%

0.953

CHF

Sinha, 2017

3.4%

4.5%

0.5939

aFIB

Sinha, 2017

7.0%

15.0%

0.0083

Alcoolism

Mallet, 2009

24 (96%)

41 (95%)

ND

Other cancer

Mallet, 2009

3 (12%)

10 (22%)

0.46

Kaplan-Feinstein grade

(severe comorbidity)

Funk, 2002

1 (4.8%)

5 (23.8%)

0.196

  1. aFIB atrial fibrillation, CAD Cardiac artery disease, CHF Chronic heart failure, COPD Chronic obstructive pulmonary disease, CVD Cardiovascular disease, DM Diabetes mellitus, DLP Dyslipidemia, HTA Hypertension
  2. Bold = Statistically significant, p-value ≤ 0.05