Table 1 Comparison of clinicopathological characteristics between patients with or without DLN metastasis
Characteristics | DLN-positive (n = 19) | DLN-negative (n = 173) | P value |
|---|---|---|---|
Female %(n) | 42.1 (8) | 72.3 (125) | 0.007 |
Age ≥ 45 years %(n) | 31.6 (6) | 56.1 (97) | 0.042 |
Tumor size ≥ 1 cm %(n) | 73.7 (14) | 28.3 (49) | < 0.001 |
Tumor distribution | 0.152 | ||
left side %(n) | 21.1 (4) | 32.4 (56) | |
right side %(n) | 42.1 (8) | 50.3 (87) | |
double side %(n) | 36.8 (7) | 17.3 (30) | |
Tumor location | 0.443 | ||
isthmus/upper third %(n) | 31.6 (6) | 28.9 (50) | |
middle third %(n) | 26.3 (5) | 40.5 (70) | |
lower third %(n) | 42.1 (8) | 30.6 (53) | |
Multifocality %(n) | 68.4 (13) | 32.9 (57) | 0.002 |
Bilaterality %(n) | 36.8 (7) | 17.3 (30) | 0.061 |
ETE %(n) | 42.1 (8) | 5.2 (9) | < 0.001 |
BRAFV600E mutation %(n) | 31.6 (6) | 21.4 (37) | 0.383 |
Hashimoto’s thyroiditis %(n) | 52.6 (10) | 33.5 (58) | 0.098 |
Tg level (ng/ml) | 24.32 ± 28.70 | 24.22 ± 35.22 | 0.991 |
Tg-Ab level (IU/ml) | 95.56 ± 164.79 | 83.66 ± 167.50 | 0.769 |
TPO level (IU/L) | 45.29 ± 58.74 | 43.53 ± 93.32 | 0.936 |
TSH level (mIU/L) | 2.69 ± 1.50 | 2.90 ± 1.65 | 0.590 |
CLNM %(n) | 89.4 (17) | 32.4 (56) | < 0.001 |
Lymph nodes dissected (n) | 5.32 ± 2.34 | 4.62 ± 2.94 | 0.320 |
Metastatic lymph nodes (n) | 3.42 ± 1.84 | 0.84 ± 1.78 | < 0.001 |
LLNM %(n) | 26.3 (5) | 4.6 (8) | 0.004 |
Mean no. of LLNM (n) | 1.16 ± 2.34 | 0.21 ± 1.11 | 0.099 |