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Table 1 Previous Case Reports of Head and Neck Cutaneous Ischemia Secondary to CAD

From: A case report of severe nasal ischemia from cold agglutinin disease and a novel treatment protocol including HBOT

Authors

Involved Region(s)

Treatment Regimen

Outcome

Poldre and collagues (1985) [4]

Nasal tip, toes, fingers

Plasmapheresis, sulfinpyrazone, dipyridamole, prednisone

Loss of 8 toes, no comment regarding outcome of nasal tip ischemia

Oh and colleagues (2009) [5]

Cheek, thigh

ASA (100 mg/day), supportive wound care

Partial resolution, with some necrosis leading to permanent scarring

Jeskowiak & George (2013) [6]

Ear

Heparin, isoprost, plasmapheresis and surgical debridement

Initial improvement, subsequently lost to follow up

Mishra & colleagues (2013) [7]

Cheeks, nasal tip, ears, hands and buttocks

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