Table 7 MRI in surveillance of IP malignant transformation summary
Study authors | Year | Study design | Level of evidence | Study group | Intervention | Outcome | Conclusion |
|---|---|---|---|---|---|---|---|
Yan et al. [30] | 2018 | Diagnostic study | B | 76 IP patients, 66 IP-SCC patients | MRI results were compared with surgical pathology reports. | IP have higher prevalence of CCP on MRI, and higher ADC values. | Evaluation of CCP and ADC values on MRI can help differentiate benign IP from IPSCC. |
Oikawa et al. [31] | 2010 | Diagnostic study | B | 21 IP patients | Patient were staged based on MRI findings and the results were compared with pathological findings.. | The positive predictive value of MRI staging, as verified by surgical and pathological findings, was 68 to 89%. | MRI can be used to accurately predict the extent of tumor involvement and staging. |
Jeon et al. [32] | 2008 | Observational study | C | 30 IP pts., 8 with SCC, vs 128 patients with various other malignant sinonasal tumors | MR images of two groups of patients were reviewed. | CCP was found in all IPs and some of the malignant sinonasal tumors. Of patients who had IP with coexistent SCC, 4 had focal loss. | The sensitivity and specificity of using CCP to differentiate IP from other malignant tumors are 100 and 87%, respectively. CCP pattern cannot be used to discriminate IP from IP with SCC. |
Maroldi et al. [33] | 2003 | Observational study | C | 23 IP patients vs. 23 malignant tumor (9 SCC) | MR images of IP and malignant patients are reviewed and compared. | CCP are found in all IP cases by SE T1 images, and in only 1 of MTs. | A columnar pattern (CCP) is a reliable MRI indicator of IP, and reflects its histological architecture, CCP and bone erosion status can distinguish IP from malignancies. |
Wang et al. [34] | 2014 | Observational study | C | 43 IP vs. 45 malignant tumor in nasal cavity (7 SCC) | MR images of IP and malignant patients are reviewed and compared. | There were significant differences between IP and malignant tumors. Washout-type TIC had a higher sensitivity and specificity in diagnosis of malignant tumors in the nasal cavity. | Non-enhanced and static MRI combined with dynamic contrast enhanced MRI (DCE-MRI) could improve differentiation between IP and malignant tumors. |