Fig. 3From: Definition and characteristics of acute exacerbation in adult patients with chronic rhinosinusitis: a systematic reviewImmunologic characteristics of acute exacerbations in adult patients with CRS. AE, acute exacerbations; CRSwNP, chronic rhinosinusitis with nasal polyps; GM-CSF, granulocyte–macrophage colony-stimulating; VEGF, vascular endothelial growth factor; EDN, eosinophil-derived neurotoxin; MPO, myeloperoxidase; MBP, major basic protein; UA, uric acidBack to article page