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Table 3 Clinical features and therapeutic management of patients in the DM group (n = 39) based on initial presentation with DM (n = 12) or development of DM after initial diagnosis (n = 27)

From: Patient and tumor factors contributing to distant metastasis in well-differentiated thyroid cancer: a retrospective cohort study

Variable Presented with DM n (%) Developed DM after diagnosis n (%) Total n (%)
Presenting Symptom
 Pathological fracture 7 (58) _ _
 Pulmonary symptoms or incidental lung nodules 5 (42) _ _
Presenting site of DM
Lung 5 (42) 19 (70) 24 (62)
Bone 7 (58) 5 (19) 12 (31)
Brain 0 (0) 1 (3) 1 (3)
Mediastinum 0 (0) 1 (3) 1 (3)
Multiple sites 1 (3) 0 (0) 1 (3)
Multiple sites of DM 8 (67) 10 (37) 18 (46)
Treatment
1 RAI cycle 12 (100) 27 (100) 39 (100)
  > 1 RAI cycle 6 (50) 11 (41) 17 (44)
EBRT 10 (83) 12 (44) 22 (56)
Metastectomy 7 (58) 6 (22) 13 (33)
  1. DM Distant metastasis, RAI Radioactive iodine, EBRT External beam radiation therapy