Fig. 1

Significant improvements in TPS, SNOT-22 and smell identification are seen after 6 months of dupilumab in both ^InitialTPS ≤ 4 and ^InitialTPS ≥ 5 groups. Box plots indicating median total polyp score (TPS) (y-axis = score 0–8) (a), Sniffin’ Sticks 16 scores (y-axis = score 0–16) (b) and total Sino Nasal Outcome Test 22 score (SNOT-22) (y-axis = score 0–110) (c) at baseline and after 6 months of dupilumab therapy (x-axes). Thick lines within the box plots indicate the median, the edges indicate the lower and upper quartiles and the whiskers indicate variability outside the upper and lower quartiles. Single dots represent outliers. Significant differences are indicated by stars (**: P ≤ 0.01, ***: P ≤ 0.001)