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Table 4 Associations between reflux and sleep outcomes

From: Association between oropharyngeal ph-monitoring, pepsin saliva concentration and degree of apnea–hypopnea index of obstructive sleep apnea

  

Reflux outcomes

  

Morning

Bedtime

Oral

Pharynx

Tonsil

Larynx

Total

Total

Ryan

pH < 6.5

pH < 6.5

pH < 6.5

Reflux outcomes

BMI

pepsin

pepsin

RSA

RSA

Score

RSA

RSA

RSS − 12

Score

Supine

Upright

N (tot)

Ryan score

0.385*

0.163

0.338*

0.380*

0.554***

0.382*

0.378*

0.539***

 − 0.039

Reflux pH < 6.5 supine

0.447**

0.226

0.181

0.109

0.625***

0.358*

0.525***

0.678***

0.129

Reflux pH < 6.5 upright

0.132

0.147

0.064

0.303

0.328*

0.334*

0.449**

0.474**

 − 0.092

Sleep outcomes

AHI

0.227

 − 0.106

0.402*

0.134

0.346

0.212

0.066

0.153

 − 0.204

0.237

0.281

 − 0.075

 − 0.073

N1

0.008

 − 0.044

0.301

 − 0.132

0.033

0.109

 − 0.056

 − 0.035

 − 0.044

 − 0.115

 − 0.088

 − 0.118

 − 0.031

N2

0.106

 − 0.071

 − 0.108

0.238

0.192

0.027

0.189

0.249

0.084

 − 0.009

0.295

0.078

0.064

N3

0.044

0.185

 − 0.188

0.217

0.001

 − 0.023

0.044

0.099

0.070

 − 0.103

0.084

0.050

 − 0.007

Paradoxical sleep

0.014

 − 0.415*

0.025

 − 0.095

0.190

 − 0.152

 − 0.319

 − 0.076

0.084

 − 0.230

 − 0.121

 − 0.279

 − 0.188

Arousal (N)

0.392*

0.167

0.299

0.099

0.118

0.369*

0.204

0.204

 − 0.098

0.054

0.202

0.058

 − 0.024

Arousal (N/h)

0.289

0.099

0.321

0.022

0.035

0.172

0.148

0.106

 − 0.089

0.019

0.110

0.010

 − 0.080

Saturation < 90%

0.250

0.097

0.354*

0.019

0.088

0.265

0.063

0.084

 − 0.041

 − 0.071

0.062

0.003

 − 0.019

Epworth

0.205

 − 0.006

0.229

0.165

 − 0.014

0.115

0.210

0.141

0.040

0.081

 − 0.009

0.022

 − 0.237

Pichot

0.208

0.157

0.060

 − 0.146

0.112

0.177

 − 0.014

0.055

0.454**

0.188

0.079

 − 0.039

 − 0.108

  1. Tonsil score was the score of tongue tonsil thickening
  2. AHI apnea–hypopnea index, BMI body mass index, RSA reflux sign assessment, RSS-12 reflux symptom score-12
  3. *p < 0.05; **p < 0.01; ***p < 0.001