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  1. Original research article

    Management delays in patients with squamous cell cancer of neck node(s) and unknown primary site: a retrospective cohort study

    We aim to characterize the workup received by and identify any delays to diagnosis or treatment in patients referred to a tertiary cancer centre with the diagnosis of squamous cell carcinoma in neck node(s) an...

    Kevin Martell, Joanna Mackenzie, Warren Kerney and Harold Yeehau Lau

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:39

    Published on: 8 May 2017

  2. Original research article

    Predictors of failure of DISE-directed adenotonsillectomy in children with sleep disordered breathing

    Adenotonsillectomy (AT) is the most commonly performed procedure for sleep disordered breathing (SDB) in pediatrics. However, 20-40% of patients will have persistent signs and symptoms of SDB after AT. Drug-in...

    Noura Alsufyani, Andre Isaac, Manisha Witmans, Paul Major and Hamdy El-Hakim

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:37

    Published on: 5 May 2017

  3. Original research article

    IL-5 and IL-6 are increased in the frontal recess of eosinophilic chronic rhinosinusitis patients

    Eosinophilic chronic frontal sinusitis is difficult to treat compared with non-eosinophilic sinusitis because of recurring inflammation and polyp formation in the frontal recess after the post-operative follow...

    Kazunori Kubota, Sachio Takeno, Takayuki Taruya, Atsushi Sasaki, Takashi Ishino and Katsuhiro Hirakawa

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:36

    Published on: 2 May 2017

  4. Original research article

    Does medical school research productivity predict a resident’s research productivity during residency?

    Research productivity is an important component of the CanMEDS Scholar role and is an accreditation requirement of Canadian Otolaryngology training programs. Our objective was to determine if an association ex...

    Scott Kohlert, Laura Zuccaro, Laurie McLean and Kristian Macdonald

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:34

    Published on: 27 April 2017

  5. Original research article

    Comparison of the mechanical properties of different skin sites for auricular and nasal reconstruction

    Autologous and synthetic nasal and auricular frameworks require skin coverage. The surgeon’s decides on the appropriate skin coverage for reconstruction based on colour matching, subcutaneous tissue thickness,...

    M. F. Griffin, B. C. Leung, Y. Premakumar, M. Szarko and P. E. Butler

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:33

    Published on: 18 April 2017

  6. Original research article

    Factors associated with lingual tonsil hypertrophy in Canadian adults

    Hypertrophy of the lingual tonsil tissue in the adult patient is thought to contribute to the pathophysiology of obstructive sleep apnea. The underlying etiology of lingual tonsil hypertrophy (LTH) in the adul...

    Matthew S. Harris, Brian W. Rotenberg, Kathryn Roth and Leigh J. Sowerby

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:32

    Published on: 17 April 2017

  7. Original research article

    Using cone beam CT to assess the upper airway after surgery in children with sleep disordered breathing symptoms and maxillary-mandibular disproportions: a clinical pilot

    The surgical excision of anatomic obstructions such as adenoids, palatine or lingual tonsils are commonly performed in children with sleep disordered breathing (SDB). Imaging studies measuring airway changes p...

    Noura A. Alsufyani, Michelle L. Noga, Manisha Witmans, Irene Cheng, Hamdy El-Hakim and Paul W. Major

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:31

    Published on: 11 April 2017

  8. Original research article

    Surgical site infections following oral cavity cancer resection and reconstruction is a risk factor for plate exposure

    Plate-related complications following head and neck cancer ablation and reconstruction remains a challenging problem often requiring further management and reconstructive surgeries. We aim to identify an assoc...

    Christopher M. Yao, Hedyeh Ziai, Gordon Tsang, Andrea Copeland, Dale Brown, Jonathan C. Irish, Ralph W. Gilbert, David P. Goldstein, Patrick J. Gullane and John R. de Almeida

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:30

    Published on: 8 April 2017

  9. Review

    Systemic therapy in the curative treatment of head and neck squamous cell cancer: a systematic review

    To review the available evidence and make recommendations regarding use of systemically administered drugs in combination or in sequence with radiation (RT) and/or surgery for cure and/or organ preservation in...

    Eric Winquist, Chika Agbassi, Brandon M. Meyers, John Yoo and Kelvin K. W. Chan

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:29

    Published on: 4 April 2017

  10. Original research article

    Predictors of hearing recovery in patients with severe sudden sensorineural hearing loss

    Sudden sensorineural hearing loss (SSHL) is a disease, which severely affects the patient’s social and relational life. The underlying pathomechanisms have not been finally clarified yet and outcome is not pre...

    Daniel Weiss, Armin Julius Böcker, Mario Koopmann, Eleftherios Savvas, Matthias Borowski and Claudia Rudack

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:27

    Published on: 4 April 2017

  11. Original research article

    The T4/T3 quotient as a risk factor for differentiated thyroid cancer: a case control study

    The incidence of thyroid nodules is increasing among patients in North America. Few of these nodules harbour malignancy, thus further research is required to identify predictive markers of malignant thyroid di...

    Mark Sasson, Emily Kay-Rivest, Rami Shoukrun, Anca Florea, Michael Hier, Veronique-Isabelle Forest, Michael Tamilia and Richard J. Payne

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:28

    Published on: 4 April 2017

  12. Original research article

    The first Canadian experience with the Afirma® gene expression classifier test

    Thyroid nodules are common and often benign, although prove to be malignant upon surgical pathology in 5–15% of cases. When assessed with ultrasound-guided fine-needle aspiration (USFNA), 15–30% of the nodules...

    Emily Kay-Rivest, Jamie Tibbo, Sarah Bouhabel, Michael Tamilia, Rebecca Leboeuf, Veronique-Isabelle Forest, Michael P. Hier, Loren Savoury and Richard J. Payne

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:25

    Published on: 4 April 2017

  13. Original research article

    Can floseal™ be applied safely during otologic surgery? Assessment of ototoxicity in a chinchilla animal model

    In otologic surgery good visualization is paramount, and patients with bleeding diatheses or who need to be anti-coagulated can present a significant challenge. Here, we determine whether Floseal™, a hemostati...

    Carol Nhan, Aren Bezdjian, Abdullah Alarfaj and Sam J. Daniel

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:24

    Published on: 29 March 2017

  14. Original research article

    Incidence and burden of comorbid pain and depression in patients with chronic rhinosinusitis awaiting endoscopic sinus surgery in Canada

    This study sheds important light on the association between sino-nasal symptoms and global quality of life in patients with chronic rhinosinusitis waiting for endoscopic sinus surgery. Using patient-reported i...

    Bassem M. N. Hanna, R. Trafford Crump, Guiping Liu, Jason M. Sutherland and Arif S. Janjua

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:23

    Published on: 27 March 2017

  15. Original research article

    Thyroid incidentalomas on 18FDG-PET/CT: a metabolico-pathological correlation

    Thyroid incidentaloma is defined as an unsuspected thyroid lesion found on imaging study or while performing a surgery non-related to the thyroid gland. Most recent scientific literature tends to demonstrate a...

    N. Hagenimana, J. Dallaire, É. Vallée and M. Belzile

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:22

    Published on: 21 March 2017

  16. Short report

    Associations of FoxP3 gene polymorphisms with severe recurrent respiratory papillomatosis in Korean patients

    FoxP3 is the most dependable marker for regulatory T cells which play a major role in immune tolerance. Foxp3 gene polymorphisms were associated with various autoimmune diseases and clearance of viral infectio...

    Tack-Kyun Kwon, Eun Jae Chung, Nuri Lee, Eun Youn Roh and Eun Young Song

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:21

    Published on: 15 March 2017

  17. Original research article

    Transoral robotic surgery with radial forearm free flap reconstruction: case control analysis

    The resection of large oropharyngeal tumors traditionally involves a lip-splitting mandibulotomy for adequate margin visualization and free flap reconstruction of the surgical defect. Transoral robotic surgery...

    Vincent L. Biron, Daniel A. O’Connell, Brittany Barber, Jessica M. Clark, Colin Andrews, Caroline C. Jeffery, David W. J. Côté, Jeffrey Harris and Hadi Seikaly

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:20

    Published on: 14 March 2017

  18. Review

    Measuring Cochlear Duct Length – a historical analysis of methods and results

    Cochlear Duct Length (CDL) has been an important measure for the development and advancement of cochlear implants. Emerging literature has shown CDL can be used in preoperative settings to select the proper si...

    Robert W. Koch, Hanif M. Ladak, Mai Elfarnawany and Sumit K. Agrawal

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:19

    Published on: 7 March 2017

  19. Original research article

    Mobile tablet audiometry in fluctuating autoimmune ear disease

    Autoimmune inner ear disease (AIED) is a rare condition characterized by bilateral fluctuating sensorineural hearing loss (SNHL). The labile nature of this hearing loss makes it difficult to accurately quantif...

    Scott Kohlert and Matthew Bromwich

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:18

    Published on: 7 March 2017

  20. Case report

    Tumor-to-tumor metastases: papillary thyroid carcinoma into a clear cell renal cell carcinoma

    Thyroid metastases to distant sites are uncommon incidents, most often metastasizing to the lungs and bones. Rates of metastasis to the kidney are particularly low, ranging from 2.8–3.8% for papillary and 6–20...

    Jin Soo Andy Song, S. Mark Taylor, Jonathan Trites, Matthew H. Rigby, Martin Joseph Bullock, Jennifer Merrimen, Ricardo Rendon and Robert D. Hart

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:17

    Published on: 1 March 2017

  21. Original research article

    Securing an OTL-HNS residency: how competitive is it? Comparing medical student perceptions to actual Canadian statistics

    The residency match is an important event in an aspiring physician’s career. Otolaryngology – Head and Neck Surgery (OTL-HNS) is a surgical specialty that has enjoyed high numbers of applicants to its residenc...

    E. Kay-Rivest, N. Varma, G. M. Scott, J. J. Manoukian, M. Desrosiers, J. P. Vaccani and L. H. P. Nguyen

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:16

    Published on: 27 February 2017

  22. Original research article

    The Hippo component YAP localizes in the nucleus of human papilloma virus positive oropharyngeal squamous cell carcinoma

    HPV infection causes cervical cancer, mediated in part by the degradation of Scribble via the HPV E6 oncoprotein. Recently, Scribble has been shown to be an important regulator of the Hippo signaling cascade. ...

    Faisal Alzahrani, Leanne Clattenburg, Shanmugam Muruganandan, Martin Bullock, Kaitlyn MacIsaac, Michael Wigerius, Blair A. Williams, M. Elise R. Graham, Matthew H. Rigby, Jonathan R. B. Trites, S. Mark Taylor, Christopher J. Sinal, James P. Fawcett and Robert D. Hart

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:15

    Published on: 22 February 2017

  23. Original research article

    Medialization thyroplasty versus injection laryngoplasty: a cost minimization analysis

    Medialization thyroplasty and injection laryngoplasty are widely accepted treatment options for unilateral vocal fold paralysis. Although both procedures result in similar clinical outcomes, little is known ab...

    Samantha Tam, Hongmei Sun, Sisira Sarma, Jennifer Siu, Kevin Fung and Leigh Sowerby

    Journal of Otolaryngology - Head & Neck Surgery 2017 46:14

    Published on: 20 February 2017

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